海筛素6的合成
Synthesis of cribrostatin 6.
作者信息
Markey Michael D, Kelly T Ross
机构信息
Department of Chemistry, Eugene F. Merkert Chemistry Center, Boston College, Chestnut Hill, Massachusetts 02467, USA.
出版信息
J Org Chem. 2008 Oct 3;73(19):7441-3. doi: 10.1021/jo801694w. Epub 2008 Aug 30.
PMID:18759482
Abstract
The synthesis of cribrostatin 6 (1) is described. A regioselective bromination, a biaryl coupling, and an intramolecular cyclization are the key steps in the synthesis.
摘要
本文描述了筛孔他汀6（1）的合成。区域选择性溴化、联芳基偶联和分子内环化是合成中的关键步骤。
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