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咪唑并[1,5 - ]喹啉的合成——无金属条件下的脱羧环化反应。

The synthesis of imidazo[1,5-]quinolines a decarboxylative cyclization under metal-free conditions.

作者信息

Yan Zicong, Wan Changfeng, Yang Yu, Zha Zhenggen, Wang Zhiyong

机构信息

Hefei National Laboratory for Physical Sciences at Microscale, CAS Key Laboratory of Soft Matter Chemistry & Center for Excellence in Molecular Synthesis of Chinese Academy of Sciences, Collaborative Innovation Center of Suzhou Nano Science and Technology & School of Chemistry and Materials Science, University of Science and Technology of China 230026 Hefei Anhui P. R. China

College of Chemistry and Chemical Engineering, Jiangxi Normal University 330022 Nanchang P. R. China

出版信息

RSC Adv. 2018 Jun 25;8(41):23058-23065. doi: 10.1039/c8ra03786h. eCollection 2018 Jun 21.

Abstract

An iodine-mediated decarboxylative cyclization was developed from α-amino acids and 2-methyl quinolines under metal-free conditions, affording a variety of imidazo[1,5-]quinolines with moderate to good yields.

摘要

在无金属条件下,由α-氨基酸和2-甲基喹啉开发了一种碘介导的脱羧环化反应,以中等至良好的产率得到了多种咪唑并[1,5 -]喹啉。

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