Bokhari Iram, Shah Syed Sagheer Hussain, Mehmood Zahid, Ali Syed Umer, Khan Asadullah
Department of General Surgery, Jinnah Postgraduate Medical Centre, Karachi.
J Coll Physicians Surg Pak. 2008 Jul;18(7):401-3.
To determine the frequency of tuberculosis in recurrent fistula-in-ano.
Case series.
This study was conducted in Surgical Ward-3, Jinnah Postgraduate Medical Centre, Karachi, Pakistan, from 1998 to 2007.
The study included 100 cases of recurrent fistula-in-ano not responding to conventional surgery. Patients with other co-morbidities such as diabetes mellitus, bleeding disorders or with the evidence of pulmonary, abdominal or intestinal tuberculosis were excluded from this study. Fistulogram was performed in all patients. All the patients were subjected to fistulectomy followed by histopathology of the resected specimen. Thereafter, confirmation of the disease, anti-tuberculous treatment was immediately started and response to treatment was observed after 6 months.
Out of the 100 studied patients, 11 cases had biopsy proven tuberculosis in the fistula. All the patients were male. The fistulae were low type, single and usually located posteriorly (n=9) with everted margins. Ten were located within 3 cm of anus. Fistulogram revealed single internal opening. Comparative statistics of tuberculous fistula-in-ano with fistulas due to specific inflammation revealed no major differences. The diagnosed patients of tubercular fistulae-in-ano were observed for at least 6 months after starting anti-tuberculous treatment. They all responded well to anti-tubercular treatment and the fistulae healed without any complication such as recurrence or anal stenosis within 6 months.
Tuberculosis should be suspected in case of recurrent fistulae-in-ano, so as to avoid unusual delay in the treatment and miseries to the patient. Appropriate anti-tuberculous therapy leads to healing within 6 months.
确定复发性肛瘘患者中结核病的发生率。
病例系列研究。
本研究于1998年至2007年在巴基斯坦卡拉奇真纳研究生医学中心外科3病房进行。
本研究纳入100例对传统手术无反应的复发性肛瘘患者。排除患有其他合并症(如糖尿病、出血性疾病)或有肺结核、腹部结核或肠道结核证据的患者。所有患者均进行了瘘管造影。所有患者均接受了瘘管切除术,随后对切除标本进行组织病理学检查。此后,确诊疾病后立即开始抗结核治疗,并在6个月后观察治疗反应。
在100例研究患者中,11例经活检证实瘘管存在结核。所有患者均为男性。瘘管为低位、单发,通常位于后方(n = 9),边缘外翻。10例位于距肛门3 cm以内。瘘管造影显示单一内口。结核性肛瘘与特异性炎症性肛瘘的比较统计显示无重大差异。对诊断为结核性肛瘘的患者在开始抗结核治疗后至少观察6个月。他们对抗结核治疗均反应良好,瘘管在6个月内愈合,无任何并发症,如复发或肛门狭窄。
对于复发性肛瘘患者应怀疑有结核病,以避免治疗出现异常延误和给患者带来痛苦。适当的抗结核治疗可在6个月内实现愈合。