Agada F O, Alhamarneh O, Stafford N D, Greenman J
Department of Otolaryngology, Division of Cancer, Postgraduate Medical Institute, University of Hull, Hull, UK.
J Laryngol Otol. 2009 Jan;123(1):19-28. doi: 10.1017/S0022215108003356. Epub 2008 Sep 2.
The survival of patients with head and neck squamous cell carcinoma has changed little over the last 30 years. However, with recent advances in the fields of cellular and molecular immunology, there is renewed optimism with regards to the development of novel methods of early diagnosis, prognosis estimation and treatment improvement for patients with head and neck squamous cell carcinoma. Here, we present a critical review of the recent advances in tumour immunology, and of the current efforts to apply new immunotherapeutic techniques in the treatment of head and neck squamous cell carcinoma.
在过去30年里，头颈部鳞状细胞癌患者的生存率几乎没有变化。然而，随着细胞和分子免疫学领域的最新进展，人们对开发头颈部鳞状细胞癌患者早期诊断、预后评估和治疗改善的新方法重新燃起了乐观情绪。在此，我们对头肿瘤免疫学的最新进展以及目前将新免疫治疗技术应用于头颈部鳞状细胞癌治疗的努力进行了批判性综述。
