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猪免疫系统的个体发育。

The ontogeny of the porcine immune system.

作者信息

Sinkora Marek, Butler John E

机构信息

Department of Immunology and Gnotobiology, Institute of Microbiology v.v.i., Academy of Sciences of the Czech Republic, Doly 183, 54922 Nový Hrádek, Czech Republic.

出版信息

Dev Comp Immunol. 2009 Mar;33(3):273-83. doi: 10.1016/j.dci.2008.07.011. Epub 2008 Aug 30.

DOI:10.1016/j.dci.2008.07.011
PMID:18762210
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7103207/
Abstract

Cellular and humoral aspects of the immune response develop sequentially in the fetus. During the ontogeny, the pluripotent stem cells emerge and differentiate into all hematopoietic lineages. Basic questions including the identification of the first lympho-hematopoietic sites, the origin of T and B lymphocytes, the development of different subpopulations of alphabeta T, gammadelta T and B lymphocytes as well as development of innate immunity and the acquisition of full immunological capacities are discussed here for swine and compared with other species. The description of related topics such as fertilization, morphogenesis, maternal-fetal-neonatal physiology and early neonatal development are also discussed.

摘要

免疫反应的细胞和体液方面在胎儿体内是依次发育的。在个体发育过程中，多能干细胞出现并分化为所有造血谱系。本文讨论了猪的一些基本问题，包括首个淋巴造血位点的识别、T和B淋巴细胞的起源、αβT、γδT和B淋巴细胞不同亚群的发育以及先天免疫的发育和完全免疫能力的获得，并与其他物种进行了比较。还讨论了受精、形态发生、母胎-新生儿生理学和新生儿早期发育等相关主题的描述。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d0cd/7103207/b080b5e81f20/gr7_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d0cd/7103207/9a6c2e4be7b3/gr1_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d0cd/7103207/70618222f2d1/gr2_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d0cd/7103207/bf6c37d59a9a/gr3_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d0cd/7103207/3f9db34d8bc4/gr4_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d0cd/7103207/9993c6eb50af/gr5_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d0cd/7103207/117ca285a2a0/gr6_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d0cd/7103207/b080b5e81f20/gr7_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d0cd/7103207/9a6c2e4be7b3/gr1_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d0cd/7103207/70618222f2d1/gr2_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d0cd/7103207/bf6c37d59a9a/gr3_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d0cd/7103207/3f9db34d8bc4/gr4_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d0cd/7103207/9993c6eb50af/gr5_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d0cd/7103207/117ca285a2a0/gr6_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d0cd/7103207/b080b5e81f20/gr7_lrg.jpg

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