Ramírez-Flandes Salvador, Ulloa Osvaldo
Departmento de Oceanografía, Universidad de Concepción, Casilla 160-C, Concepción, Chile.
Bioinformatics. 2008 Nov 1;24(21):2539-41. doi: 10.1093/bioinformatics/btn466. Epub 2008 Sep 1.
Phylogenetic analyses today involve dealing with computer files in different formats and often several computer programs. Although some widely used applications have integrated important functionalities for such analyses, they still work with local resources only: input/output files (users have to manage them) and local computing (users have sometimes to leave their programs, on their desktop computers, running for extended periods of time). To address these problems we have developed 'Bosque', a multi-platform client-server software that performs standard phylogenetic tasks either locally or remotely on servers, and integrates the results on a local relational database. Bosque performs sequence alignments and graphical visualization and editing of trees, thus providing a powerful environment that integrates all the steps of phylogenetic analyses.
如今的系统发育分析涉及处理不同格式的计算机文件，并且常常要使用多个计算机程序。尽管一些广泛使用的应用程序已经集成了用于此类分析的重要功能，但它们仍然仅使用本地资源：输入/输出文件（用户必须管理这些文件）以及本地计算（用户有时必须让他们在台式计算机上运行的程序长时间运行）。为了解决这些问题，我们开发了“Bosque”，这是一款多平台客户端 - 服务器软件，它可以在本地或服务器上远程执行标准的系统发育任务，并将结果集成到本地关系数据库中。Bosque 执行序列比对以及树的图形可视化和编辑，从而提供了一个集成系统发育分析所有步骤的强大环境。
