Mellergård P, Nordström C H
Department of Neurosurgery, University Hospital of Lund, Sweden.
Neurosurgery. 1991 May;28(5):709-13.
Recent laboratory results have indicated that the ischemic brain is very sensitive to minor variations in temperature. This has created new interest in hypothermia and brain temperature. There is, however, very little information available regarding human intracerebral temperature and its relation to body core temperature during normal and pathological circumstances. We therefore made continuous measurements of the temperature of the lateral ventricle in 15 neurosurgical patients utilizing a newly developed technique with copper-constantan thermocouples introduced through a plastic catheter also used for monitoring intracranial pressure. The intraventricular temperature was higher than the rectal temperature during approximately 90% of all measurements. The largest temperature gradient measured was 2.3 degrees C. Usually the difference between the temperature of the rectum and the brain was much smaller, the mean value being 0.33 degrees C. For the patients in the most severe condition, the rectal temperature was sufficiently close to the brain temperature to afford a reliable basis for adequate clinical judgment.
近期实验室结果表明，缺血性脑对温度的微小变化非常敏感。这引发了对低温疗法和脑温的新关注。然而，关于正常和病理情况下人体脑内温度及其与体核温度的关系，现有信息非常少。因此，我们利用一种新开发的技术，通过一根也用于监测颅内压的塑料导管插入铜-康铜热电偶，对15例神经外科患者的侧脑室温度进行了连续测量。在所有测量中，约90%的时间内脑室内温度高于直肠温度。测得的最大温度梯度为2.3摄氏度。通常直肠温度与脑温之间的差异要小得多，平均值为0.33摄氏度。对于病情最严重的患者，直肠温度与脑温足够接近，可为充分的临床判断提供可靠依据。
