Ogino Daisuke, Kawaji Hiroyuki, Konttinen Liisa, Lehto Matti, Rantanen Pekka, Malmivaara Antti, Konttinen Yrjö T, Salo Jari
Department of Medicine, Helsinki University Central Hospital, Biomedicum Helsinki, P.O. Box 700 (Haartmaninkatu 8), FIN-00029 HUS, Finland.
J Bone Joint Surg Am. 2008 Sep;90(9):1884-90. doi: 10.2106/JBJS.G.00147.
The number of people eighty years of age and older in developed countries is increasing, with a concomitant increased demand for total hip replacement. We analyzed the outcomes of total hip arthroplasty for patients in this age group using data from the Finnish National Arthroplasty Registry.
Data from the Finnish Arthroplasty Registry on 6540 patients (6989 hips) who were eighty years of age or older at the time of a total hip arthroplasty, performed between 1980 and 2004, were evaluated with use of survival analyses. Factors affecting survivorship rates were sought, and the reasons for revision were identified.
The mean age of the patients undergoing a primary total hip arthroplasty was 82.7 years. The mean longevity of 3065 patients who died following total hip arthroplasty was 5.1 years. With revision total hip arthroplasty for any reason as the end point, Kaplan Meier survivorship was 97% (95% confidence interval, 96% to 97%) at five years (2617 hips) and 94% (95% confidence interval, 93% to 95%) at ten years (532 hips). Of the 195 hip replacements that required revision, 183 had information on the reason for revision. Eighty-four (46%) were revised for aseptic loosening; thirty-six (20%), for recurrent dislocation; twenty-four (13%), for a periprosthetic fracture; and twenty-three (13%), for infection. Seven hundred and twenty-nine patients had undergone hybrid fixation (a cemented stem and a cementless cup). The survivorship of these replacements was significantly better than that for replacements with cementless fixation in 399 patients (p < 0.05).
In patients who had a total hip arthroplasty when they were more than eighty years old, the prevalence of aseptic loosening was less than that encountered in younger patients, but recurrent dislocation, periprosthetic fracture, and infection were more common in this age group. Cementation of the femoral stem demonstrated better long-term results than cementless fixation, indicating that it may provide better initial fixation and, therefore, longer life-in-service.
发达国家80岁及以上的人口数量正在增加,全髋关节置换的需求也随之增加。我们使用芬兰国家关节置换登记处的数据,分析了该年龄组患者全髋关节置换的结果。
利用生存分析评估了芬兰关节置换登记处1980年至2004年间进行全髋关节置换时年龄在80岁及以上的6540例患者(6989髋)的数据。寻找影响生存率的因素,并确定翻修原因。
接受初次全髋关节置换的患者平均年龄为82.7岁。全髋关节置换术后死亡的3065例患者的平均寿命为5.1年。以因任何原因进行翻修全髋关节置换作为终点,5年时(2617髋)Kaplan-Meier生存率为97%(95%置信区间,96%至97%),10年时(532髋)为94%(95%置信区间,93%至95%)。在195例需要翻修的髋关节置换中,183例有翻修原因的信息。84例(46%)因无菌性松动进行翻修;36例(20%)因反复脱位进行翻修;24例(13%)因假体周围骨折进行翻修;23例(13%)因感染进行翻修。729例患者接受了混合固定(骨水泥柄和非骨水泥杯)。这些置换的生存率明显高于399例接受非骨水泥固定置换的患者(p<0.05)。
80岁以上接受全髋关节置换的患者中,无菌性松动的发生率低于年轻患者,但该年龄组反复脱位、假体周围骨折和感染更为常见。股骨柄骨水泥固定显示出比非骨水泥固定更好的长期效果,表明它可能提供更好的初始固定,因此使用寿命更长。