Arushanyan E B, Baturin V A, Ovanesov K B
Department of the Pharmacology of the Vestibular Apparatus, State Medical Institute, Stavropol.
Neurosci Behav Physiol. 1991 Mar-Apr;21(2):145-9. doi: 10.1007/BF01182890.
A peptide preparation of the pineal, epithalamin, when administered chronically, exerts a modulating influence on the diurnal fluctuations of the motoric activity of rats. It also decreases the amplitude of apomorphine stereotypy and induces a restructuring of a modulatory character in its rhythmic structure. It is hypothesized that the pineal peptides participate in the maintenance of homeostasis by means of the stabilization of rhythmic processes of various periods.
松果体的一种肽制剂——epithalamin,长期给药时,会对大鼠运动活动的昼夜波动产生调节作用。它还会降低阿扑吗啡刻板行为的幅度,并在其节律结构中诱导出一种调节性的重组。据推测,松果体肽通过稳定不同周期的节律过程来参与体内稳态的维持。