宫腔内人工授精：时机是否正确？
Intrauterine insemination: is the timing correct?
作者信息
Kucuk Tansu
机构信息
Department of Obstetrics & Gynecology, GATA School of Medicine, Ankara, Turkey.
出版信息
J Assist Reprod Genet. 2008 Aug;25(8):427-30. doi: 10.1007/s10815-008-9247-9. Epub 2008 Sep 2.
Abstract
OBJECTIVE
To evaluate the impact of follicle rupture on pregnancy rate in intrauterine insemination.
MATERIAL AND METHOD
Retrospective cohort study. Evidence of follicle rupture was assessed by transvaginal ultrasonography following IUI. Two hundred ninety-six couples with unexplained infertility and 121 couples with male factor subfertility were included. Results of 578 cycles were analyzed here.
RESULT
Clinical pregnancy rate was 23.5% (64/272) in the group when follicle rupture was evident by transvaginal ultrasonography, while it was only 8.8% (27/306) when follicle rupture was not evident (p < 0.001).
CONCLUSION
Postponing IUI until observation of follicle rupture may yield a higher pregnancy rate.
摘要
目的
评估卵泡破裂对宫腔内人工授精妊娠率的影响。
材料与方法
回顾性队列研究。在宫腔内人工授精后通过经阴道超声评估卵泡破裂的证据。纳入了296对不明原因不孕症夫妇和121对男性因素亚生育夫妇。分析了578个周期的结果。
结果
经阴道超声显示卵泡明显破裂的组临床妊娠率为23.5%（64/272），而卵泡未明显破裂时临床妊娠率仅为8.8%（27/306）（p<0.001）。
结论
将宫腔内人工授精推迟至观察到卵泡破裂可能会获得更高的妊娠率。
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