Gosewehr J A, Julian T M, O'Connell B J
Department of Obstetrics and Gynecology, University of Wisconsin Medical School, Madison.
Obstet Gynecol. 1991 Sep;78(3 Pt 1):440-3.
In a series of 39 patients undergoing cervical conization, the Cytobrush was used to determine whether dysplasia involved the endocervical canal. To improve the specificity of the Cytobrush for this purpose, a sleeve was designed to guide the brush into the endocervical canal in order to minimize contamination from ectocervical lesions. Both the unsleeved and sleeved Cytobrush demonstrated good sensitivity for detecting dysplasia within the endocervical canal (89 and 95%, respectively). The sleeved Cytobrush demonstrated greater specificity than the unsleeved Cytobrush (90 versus 60%; P less than .05). Compared with endocervical curettage, the Cytobrush used in conjunction with the described "cytosleeve" offers an inexpensive, less painful, and accurate method of determining endocervical involvement of dysplasia.
在一组39例接受宫颈锥切术的患者中，使用细胞刷来确定发育异常是否累及宫颈管。为提高细胞刷在此方面的特异性，设计了一个套管，用于引导刷子进入宫颈管，以尽量减少来自宫颈外病变的污染。未使用套管的细胞刷和使用套管的细胞刷在检测宫颈管内发育异常方面均显示出良好的敏感性（分别为89%和95%）。使用套管的细胞刷比未使用套管的细胞刷具有更高的特异性（分别为90%和60%；P<0.05）。与宫颈管刮除术相比，结合所述“细胞套管”使用的细胞刷提供了一种廉价、疼痛较轻且准确的方法来确定发育异常是否累及宫颈管。
