Jhas Sumit, Tuli Sagun
Department of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
J Neurosurg Spine. 2008 Aug;9(2):196-9. doi: 10.3171/SPI/2008/9/8/196.
The authors report the case of a 54-year-old woman who presented with an intraparenchymal granuloma in her lower thoracic spinal cord. On imaging studies there was an intramedullary enhancement at the left dorsal aspect of the cord immediately adjacent to the tip of an intrathecal arachnoid catheter used for intraspinal drug therapy. At surgery, it was apparent that once this superficial component of the catheter and inflammatory mass was removed, there was a granulomatous component that extended into the spinal cord. A 5-mm caseating chalklike granuloma was carefully dissected away. To the authors' knowledge, this is the first reported case of an intrathecal catheter-tip granuloma growing inside the spinal cord parenchyma.
作者报告了一例54岁女性病例,该患者下胸段脊髓出现实质内肉芽肿。影像学检查显示,在脊髓左背侧紧邻用于脊髓内药物治疗的鞘内蛛网膜导管尖端处有髓内强化。手术中发现,一旦移除导管和炎性肿块的浅表部分,就有一个延伸至脊髓的肉芽肿成分。一个5毫米的干酪样粉笔状肉芽肿被小心地剥离。据作者所知,这是首例报道的鞘内导管尖端肉芽肿生长于脊髓实质内的病例。