Hanai Shuji, Hamasaka Yasutaka, Ishida Norio
Clock Cell Biology Research Group, Institute for Biological Resources and Functions, National Institute of Advanced Industrial Science and Technology, Higashi, Tsukuba, Ibaraki, Japan.
Neuroreport. 2008 Sep 17;19(14):1441-4. doi: 10.1097/WNR.0b013e32830e4961.
Like most other insects, Drosophila visual system is sensitive to the spectrum of light from ultraviolet to green but is insensitive to red light. The circadian rhythms of Drosophila, however, can be entrained by red light through unknown mechanisms. Here, we discovered the corresponding organ and photopigments responsible for the circadian entrainment of Drosophila to red light from light emitting diode. The entrainment was eliminated by the loss of photic input from compound eyes using eya(2) or norpA(p24). We also found that the double Rhodopsin 1 (ninaE) and Rhodopsin mutant was not entrained to red light. These results indicate that Drosophila can entrain the circadian rhythm to red light through Rhodopsin 1 and Rhodopsin 6 in compound eyes.
与大多数其他昆虫一样，果蝇的视觉系统对从紫外线到绿光的光谱敏感，但对红光不敏感。然而，果蝇的昼夜节律可以通过未知机制被红光所调节。在这里，我们发现了负责果蝇对发光二极管发出的红光进行昼夜节律调节的相应器官和光色素。使用eya(2)或norpA(p24)消除复眼的光输入后，这种调节作用就消失了。我们还发现，双视紫红质1（ninaE）和视紫红质突变体不会被红光调节。这些结果表明，果蝇可以通过复眼中的视紫红质1和视紫红质6将昼夜节律调节至红光。
