Baumeister Steffen, Follmar Keith E, Zenn Michael R, Erdmann Detlev, Levin L Scott
Durham, N.C. From the Division of Plastic, Reconstructive, Maxillofacial, and Oral Surgery, Duke University Medical Center.
Plast Reconstr Surg. 2008 Sep;122(3):962-971. doi: 10.1097/PRS.0b013e3181811ca0.
Free vascularized tissue transfer is generally associated with high success rates, but failures do occur. After a flap failure, the decision is often made to perform a second, reoperative free flap.
A retrospective review of all microsurgical free tissue transfers performed at the authors' institution identified 13 patients who underwent a second, reoperative free flap after a failed primary flap. The records of these patients were reviewed, with particular emphasis on identifying changes in treatment strategy between the initially failed and the reoperative free flap.
Thirteen patients were identified as having undergone a reoperative free flap. In nine of 13 primary free flaps, at least one likely cause for the failure was identified (69 percent). In the approach to the second free flap, strategy changes were performed in 10 of 13 cases (77 percent); 11 were successful (85 percent). One of the two patients with a failed reoperative free flap underwent a third attempt at free tissue transfer, which also failed.
The authors' overall approach to the failed free flap includes the following four steps: (1) reconsideration of the need for vascularized free tissue transfer, (2) a sensitive psychosocial approach to the patient and family, (3) analysis of the cause of the first flap failure, and (4) change in microsurgical strategy. Based on the authors' experience, they consider two previously failed free flaps without an obvious cause to be a contraindication to a third attempt.
游离血管化组织移植通常成功率较高,但失败情况确实会发生。皮瓣失败后,通常会决定进行第二次游离皮瓣再次手术。
对作者所在机构进行的所有显微外科游离组织移植进行回顾性研究,确定了13例在初次皮瓣失败后接受第二次游离皮瓣再次手术的患者。对这些患者的记录进行了审查,特别强调确定初次失败的皮瓣与再次手术的游离皮瓣之间治疗策略的变化。
确定有13例患者接受了游离皮瓣再次手术。在13例初次游离皮瓣中,有9例(69%)至少确定了一个可能的失败原因。在进行第二次游离皮瓣手术时,13例中有10例(77%)改变了策略;11例成功(85%)。在2例游离皮瓣再次手术失败的患者中,有1例进行了第三次游离组织移植尝试,但也失败了。
作者对游离皮瓣失败的总体处理方法包括以下四个步骤:(1)重新考虑是否需要进行血管化游离组织移植;(2)对患者及其家属采取敏感的心理社会方法;(3)分析第一次皮瓣失败的原因;(4)改变显微外科策略。根据作者的经验,他们认为两次先前游离皮瓣失败且无明显原因是第三次尝试的禁忌证。