Vabres Pierre
Service de dermatologie, CHU de Dijon, F-21079 Dijon Cedex, France.
Presse Med. 2008 Oct;37(10):1480-3. doi: 10.1016/j.lpm.2008.05.009. Epub 2008 Sep 2.
Hereditary syndromes of predisposition to skin cancer are rare conditions with several different modes of transmission (autosomal recessive, dominant or X-linked). These conditions predispose principally to skin tumors, but sometimes, although more rarely, to some visceral tumors. The clinical and histologic characteristics of the tumors observed in these conditions are generally identical to those of sporadic forms. They are distinguished, however, by their multiple number and their earlier onset.
遗传性皮肤癌易感性综合征是罕见病症，有几种不同的遗传模式（常染色体隐性、显性或X连锁）。这些病症主要易患皮肤肿瘤，但有时，尽管较为罕见，也会易患一些内脏肿瘤。在这些病症中观察到的肿瘤的临床和组织学特征通常与散发性肿瘤相同。然而，它们的区别在于数量众多且发病较早。
