Kutuya Naoki, Ozaki Yutaka, Kurosaki Yoshihisa
Department of Radiology, Juntendo University, School of Medicine, Bunkyo-ku, Tokyo, 113-8421, Japan.
Radiat Med. 2008 Aug;26(7):389-95. doi: 10.1007/s11604-008-0246-7. Epub 2008 Sep 4.
The purpose of this prospective study was to perform quantitative multidetector computed tomography (MDCT) analysis of pulmonary solid nodules using three parameters (long-short ratio, compactness, and intranodular CT number) and to evaluate the usefulness of each parameter in the differentiation of the nodules.
Seventy solitary pulmonary nodules with a long axis length of 5-30 mm were examined using one multidetector CT (MDCT) system and one three-dimensional (3D) system, and the findings regarding the three parameters were statistically analyzed among five diseases (hamartoma, organizing pneumonia, adenocarcinoma, squamous cell carcinoma, and metastasis).
The long-short ratio of the pulmonary nodule showed no significant differences among five diseases. The compactness showed significant differences (P < 0.05) in five pairs of diseases. Intranodular CT number showed significant differences (P < 0.05) in three pairs of diseases.
Our results are insufficient for the complete differentiation of pulmonary solid nodules. However, among the three parameters, compactness and intranodular CT number contribute somewhat to the differentiation of pulmonary nodules.
本前瞻性研究的目的是使用三个参数（长短比、致密性和结节内CT值）对肺实性结节进行定量多排螺旋计算机断层扫描（MDCT）分析，并评估每个参数在鉴别结节中的有用性。
使用一台多排螺旋CT（MDCT）系统和一台三维（3D）系统对70个长轴长度为5 - 30 mm的孤立性肺结节进行检查，并对五种疾病（错构瘤、机化性肺炎、腺癌、鳞状细胞癌和转移瘤）的三个参数结果进行统计学分析。
肺结节的长短比在五种疾病之间无显著差异。致密性在五组疾病对中显示出显著差异（P < 0.05）。结节内CT值在三组疾病对中显示出显著差异（P < 0.05）。
我们的结果不足以完全鉴别肺实性结节。然而，在这三个参数中，致密性和结节内CT值对肺结节的鉴别有一定贡献。
