Drayer J A, Vittitoe N F, Vargas-Voracek R, Baydush A H, Ravin C E, Floyd C E
School of Medicine, Duke University, Durham, NC, USA.
Acad Radiol. 1998 Sep;5(9):613-9. doi: 10.1016/s1076-6332(98)80297-3.
This study was performed to determine physical characteristics of areas on chest radiographs that are suspicious but not definitive for the presence of a pulmonary nodule and the characteristics of areas that contain an obvious nodule.
Two groups of patients were identified: those who had an area at plain radiography that was suspicious for a pulmonary nodule and underwent fluoroscopy for further evaluation (138 patients, 142 areas) and those who had an obvious nodule at plain radiography who underwent computed tomography for further evaluation (72 patients, 97 areas). The measured characteristics of the region of interest included size, circularity, compactness, contrast, and location.
A comparison of the data show that while there was some difference between these groups of patients with regard to location of the nodules, there were essentially no differences with regard to size, circularity, compactness, and contrast of the regions of interest.
Size, circularity, compactness, contrast, and location are not sufficient to distinguish pulmonary nodules from other suspicious regions on the chest radiograph.
本研究旨在确定胸部X光片上可疑但不能确诊为肺结节区域的物理特征以及包含明显结节区域的特征。
确定了两组患者：一组在平片上有可疑肺结节区域并接受荧光透视进一步评估（138例患者，142个区域），另一组在平片上有明显结节并接受计算机断层扫描进一步评估（72例患者，97个区域）。感兴趣区域的测量特征包括大小、圆形度、紧密度、对比度和位置。
数据比较显示，虽然这些患者组在结节位置方面存在一些差异，但在感兴趣区域的大小、圆形度、紧密度和对比度方面基本没有差异。
大小、圆形度、紧密度、对比度和位置不足以将肺结节与胸部X光片上的其他可疑区域区分开来。
