Mureebe Leila, Egorova Natalia, Giacovelli Jeannine K, Gelijns Annetine, Kent K Craig, McKinsey James F
Division of Vascular Surgery, New York Presbyterian Hospital, Columbia College of Physicians and Surgeons, Weill Medical College of Cornell University, New York, NY 10032, USA.
J Vasc Surg. 2008 Nov;48(5):1101-7. doi: 10.1016/j.jvs.2008.06.031. Epub 2008 Sep 4.
This study evaluated trends in hospitalizations, treatment, and mortality of ruptured abdominal aortic aneurysms (rAAAs) in the United States Medicare population.
The Medicare inpatient database (1995 through 2006) was reviewed for patients with rAAA and AAA by using International Classification of Disease (9th Clinical Modification) codes for rAAA and AAA. Proportions and trends were analyzed by chi(2) analysis, continuous variables by t test, and trends by the Cochran-Armitage test.
During the study period, hospitalizations with the diagnoses of rAAA declined from 23.2 to 12.8 per 100,000 Medicare beneficiaries (P < .0001), as did repairs of rAAA (15.6 to 8.4 per 100,000; P < .0001). No change was observed in AAA elective repairs. The 30-day mortality rate after open repair of rAAA decreased by 4.9% (from 39.6% to 34.7%; P = .0007 for trend) for the age group 65 to 74 and by 2.4% (from 52.9% to 50.5%, P = .0008) for the age group > or =75. Perioperative mortality after endovascular repair diminished by 13.6% (from 43.5% in 2001 to 29.9% in 2006; P = .0020). Mortality among women was higher than among men (51.1% vs 40.0% in 2006). The demographics of patients treated for rAAA changed to include a greater proportion of women and patients aged > or =75 years.
A significant decrease has occurred in the number of patients who have a diagnosis of rAAA and undergo treatment, but there has been no change in repairs of AAA. The perioperative mortality rate has improved due to the introduction of endovascular repair and a small but progressive improvement in survival after open repair for patients aged 65 to 74 years.
本研究评估了美国医疗保险人群中腹主动脉瘤破裂(rAAA)患者的住院治疗情况、治疗方式及死亡率趋势。
通过使用国际疾病分类(第9版临床修订本)中rAAA和AAA的编码,对医疗保险住院数据库(1995年至2006年)中的rAAA和AAA患者进行回顾性分析。采用卡方分析评估比例和趋势,t检验分析连续变量, Cochr an - Armitage检验分析趋势。
在研究期间,每10万名医疗保险受益人中,诊断为rAAA的住院人数从23.2降至12.8(P <.0001),rAAA修复手术人数也从15.6降至8.4(每10万人;P <.0001)。AAA择期修复手术人数无变化。65至74岁年龄组rAAA开放修复术后30天死亡率下降了4.9%(从39.6%降至34.7%;趋势P =.0007),≥75岁年龄组下降了2.4%(从52.9%降至50.5%,P =.0008)。血管腔内修复术后围手术期死亡率下降了13.6%(从2001年的43.5%降至2006年的29.9%;P =.0020)。女性死亡率高于男性(2006年为51.1%对40.0%)。接受rAAA治疗的患者人口统计学特征发生变化,女性和≥75岁患者的比例增加。
诊断为rAAA并接受治疗的患者数量显著减少,但AAA修复手术数量无变化。由于血管腔内修复技术的引入,围手术期死亡率有所改善,且65至74岁患者开放修复术后生存率有小幅但持续的提高。