Li Kun, Zhang Kewei, Li Tianxiao, Zhai Shuiting
Department of Vascular and Endovascular Surgery, Henan Provincial People's Hospital, Fuwai Central China Cardiovascular Hospital, NO.7 Weiwu Road, Zhengzhou, 450003, Henan, People's Republic of China.
BMC Cardiovasc Disord. 2018 Apr 3;18(1):60. doi: 10.1186/s12872-018-0793-5.
There is a lack of information on the epidemiological data and risk factors associated with abdominal aortic aneurysm (AAA) in Chinese population. We reported the primary results from screening five-community population in Middle China for AAA.
From March 2014 to October 2015, an AAA screening program was performed in three urban and two rural communities. These communities were randomly selected. All at-risk residents (a total of 6925) aged 40 years or older were invited to attend an ultrasound scan for AAA. At-risk population was defined as having a family history of first-degree relative diagnosed with AAA; or smoking and aged 55 years or older; or having a history of CAD, cerebrovascular disease, hypercholesterolemia, obesity (BMI ≧ 26 kg/m) or hypertension.
The study investigated 5402 subjects and the mean age of them was 61.2 ± 10.4 years old. It included 2847 women aged 62.5 ± 10.4 years and 2555 men aged 59.7 ± 10.2 years. The mean maximum infrarenal aortic diameter (Max-IAD) was 15.0 ± 2.7 mm (from 4.1 to 51.5 mm). Eighteen people (aged 68.0 ± 10.4 years) with AAAs were detected (prevalence rate was 0.33%), and the prevalence rate in males was higher than in females (0.55% vs 0.14%, respectively, P = 0.009). Additionally, the screened subjects aged 55 to 75 years had a higher prevalence rate of AAA than other age groups (0.51% vs 0.11%, respectively, P = 0.016).
The mean Max-IAD of the screened population in Middle China was apparently small by comparison with other reports. The result of low prevalence rate of AAA didn't support routine screening in Chinese population. The at-risk males aged 55 to 75 years should be targeted for further screening.
中国人群中关于腹主动脉瘤（AAA）的流行病学数据及相关危险因素的信息匮乏。我们报告了在中国中部五个社区人群中进行AAA筛查的初步结果。
2014年3月至2015年10月，在三个城市社区和两个农村社区开展了AAA筛查项目。这些社区是随机选取的。所有40岁及以上的高危居民（共6925人）被邀请参加AAA超声扫描。高危人群定义为有一级亲属被诊断为AAA的家族史；或吸烟且年龄在55岁及以上；或有冠心病、脑血管疾病、高胆固醇血症、肥胖（BMI≧26kg/m）或高血压病史。
该研究调查了5402名受试者，他们的平均年龄为61.2±10.4岁。其中包括2847名年龄为62.5±10.4岁的女性和2555名年龄为59.7±10.2岁的男性。肾下腹主动脉平均最大直径（Max-IAD）为15.0±2.7mm（范围为4.1至51.5mm）。检测到18例AAA患者（年龄为68.0±10.4岁）（患病率为0.33%），男性患病率高于女性（分别为0.55%和0.14%，P=0.009）。此外，55至75岁的筛查对象AAA患病率高于其他年龄组（分别为0.51%和0.11%，P=0.016）。
与其他报告相比中国中部筛查人群的平均Max-IAD明显较小。AAA患病率低的结果不支持在中国人群中进行常规筛查。55至75岁的高危男性应作为进一步筛查的对象。
