Shadow enhancers as a source of evolutionary novelty.
作者信息
Hong Joung-Woo, Hendrix David A, Levine Michael S
机构信息
Department of Molecular and Cell Biology, Division of Genetics, Genomics, and Development, Center for Integrative Genomics, University of California, Berkeley, CA 94720, USA.
出版信息
Science. 2008 Sep 5;321(5894):1314. doi: 10.1126/science.1160631.
Abstract
摘要
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本文引用的文献
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The evolution of gene regulation underlies a morphological difference between two Drosophila sister species.基因调控的进化是果蝇两个姐妹物种之间形态差异的基础。
Cell. 2008 Mar 7;132(5):783-93. doi: 10.1016/j.cell.2008.01.014.
2
Whole-genome ChIP-chip analysis of Dorsal, Twist, and Snail suggests integration of diverse patterning processes in the Drosophila embryo.对背腹因子、扭曲蛋白和蜗牛蛋白进行全基因组芯片分析，结果表明果蝇胚胎中多种模式形成过程存在整合现象。
Genes Dev. 2007 Feb 15;21(4):385-90. doi: 10.1101/gad.1509607.
3
A functional screen for sonic hedgehog regulatory elements across a 1 Mb interval identifies long-range ventral forebrain enhancers.在1兆碱基区间内对音猬因子调控元件进行的功能筛选鉴定出了远程腹侧前脑增强子。
Development. 2006 Feb;133(4):761-72. doi: 10.1242/dev.02239. Epub 2006 Jan 11.
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Whole-genome analysis of dorsal-ventral patterning in the Drosophila embryo.果蝇胚胎背腹模式形成的全基因组分析。
Cell. 2002 Nov 27;111(5):687-701. doi: 10.1016/s0092-8674(02)01087-5.
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Redundant and unique roles of two enhancer elements in the TCRgamma locus in gene regulation and gammadelta T cell development.TCRγ基因座中两个增强子元件在基因调控和γδT细胞发育中的冗余和独特作用。
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Genome-wide analysis of clustered Dorsal binding sites identifies putative target genes in the Drosophila embryo.对成簇的背侧结合位点进行全基因组分析，可确定果蝇胚胎中的假定靶基因。
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