Levinson M L, Lipsy R J, Fuller D K
Department of Pharmacy, University of Michigan Medical Center, Ann Arbor.
DICP. 1991 Jun;25(6):657-61. doi: 10.1177/106002809102500617.
Fluoxetine, an inhibitor of serotonin reuptake, was released by the Food and Drug Administration in 1988 and was among the most prescribed drugs for that year. Although fluoxetine has been promoted as a safe antidepressant, a recent literature search revealed a number of case reports of adverse effects and drug interactions attributed to its use. This review familiarizes healthcare professionals with some of the currently known interactions and adverse effects and suggests ways of avoiding such events in clinical practice.
氟西汀是一种血清素再摄取抑制剂，于1988年由美国食品药品监督管理局批准上市，是当年处方量最多的药物之一。尽管氟西汀一直被宣传为一种安全的抗抑郁药，但最近的文献检索发现了一些与使用该药物相关的不良反应和药物相互作用的病例报告。这篇综述旨在让医疗保健专业人员熟悉一些目前已知的相互作用和不良反应，并提出在临床实践中避免此类事件的方法。
