Mørkeberg J S, Belhage B, Damsgaard R
Anesthesiology, Bispebjerg Hospital, Copenhagen NV, Denmark.
Int J Sports Med. 2009 Feb;30(2):130-8. doi: 10.1055/s-2008-1038842. Epub 2008 Sep 4.
In 2006, a couple of professional cycling teams initiated their own testing programs. The objective of this study is to describe fluctuations in commonly measured blood parameters among top-level riders. From December 12th 2006 to November 30th 2007, a total of 374 blood samples and 287 urine samples were obtained from 28 elite, male cyclists. Blood was analyzed for hematocrit (Hct), hemoglobin concentration ([Hb]) and % reticulocytes. Seventy-six percent of all samples were collected out-of-competition (OOC). From December 2006 to September 2007, the average Hct and [Hb] decreased by 4.3 percent point and 1.3 g/dL, respectively. After the end of the competitive season, the values increased back to baseline levels. During the Tour de France, the [Hb] decreased by 11.5 %, with individual decreases ranging from 7.0 to 20.6 %. Hct and [Hb] values were lower in-competition (40.9 % and 14.1 g/dL) compared to OOC (43.2 % and 15.0 g/dL) and pre-competition (43.5 % and 14.9 g/dL). Our results suggest that when interpreting blood sample results in an anti-doping context, the sample timing (OOC, pre- or in-competition) and time of year should be kept in mind.
2006年，几支职业自行车队启动了自己的检测项目。本研究的目的是描述顶级车手常见血液参数的波动情况。从2006年12月12日至2007年11月30日，共从28名精英男性自行车运动员身上采集了374份血样和287份尿样。对血液进行了血细胞比容（Hct）、血红蛋白浓度（[Hb]）和网织红细胞百分比的分析。所有样本中有76%是在非比赛期间（OOC）采集的。从2006年12月到2007年9月，平均血细胞比容和[Hb]分别下降了4.3个百分点和1.3 g/dL。比赛赛季结束后，这些值回升至基线水平。在环法自行车赛期间，[Hb]下降了11.5%，个体下降幅度在7.0%至20.6%之间。与非比赛期间（43.2%和15.0 g/dL）和比赛前（43.5%和14.9 g/dL）相比，比赛期间的血细胞比容和[Hb]值较低（40.9%和14.1 g/dL）。我们的结果表明，在反兴奋剂背景下解释血样结果时，应考虑样本采集时间（非比赛期间、比赛前或比赛中）和一年中的时间。
