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大鼠基底外侧杏仁核中的被动回避条件反射与单位活动

Passive avoidance conditioning and unitary activity in the basolateral amygdaloid nucleus of the rat.

作者信息

Yajeya J, Patino A, Riolobos A S, Criado J M, De La Fuente A

机构信息

Department of Physiology and Pharmacology, University of Salamanca, Spain.

出版信息

Acta Physiol Scand. 1991 Apr;141(4):549-53. doi: 10.1111/j.1748-1716.1991.tb09116.x.

DOI:10.1111/j.1748-1716.1991.tb09116.x
PMID:1877353
Abstract

Single unit activity was recorded in the basolateral nucleus of amygdala in rats in a passive avoidance test. Simultaneously, visual control of exploratory behaviour was carried out. Prior to establishing the conditioning, the mean frequency of the unit discharge was 14 Hz (SD = 9) and 1 minute after conditioning this unit activity decreased to values close to zero; later on (24 and 48 hours), a progressive recovery of the discharge was observed. Behavioural changes were also detected. The long term recovery of unit activity follows the time course of the extinction process. The possible significance of these findings is discussed in relation to some of the functional roles of this nucleus.

摘要

在被动回避试验中记录大鼠杏仁核基底外侧核的单单位活动。同时,对探索行为进行视觉控制。在建立条件反射之前,单位放电的平均频率为14赫兹(标准差=9),在条件反射后1分钟,该单位活动降至接近零的值;随后(24小时和48小时),观察到放电逐渐恢复。还检测到行为变化。单位活动的长期恢复遵循消退过程的时间进程。结合该核的一些功能作用讨论了这些发现的可能意义。

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