Sugiura T, Ito M, Mizokami K
Department of Ophthalmology, School of Medicine, Kobe University, Japan.
Nippon Ganka Gakkai Zasshi. 1991 Apr;95(4):343-7.
The relation between the optic disc appearances and the progression of visual field defects was studied by retrospective case review of 148 eyes of 74 patients with a diagnosis of low-tension glaucoma (LTG). Visual fields were tested by a Goldmann perimeter and the subjects were divided into two groups, i.e. 43 eyes (29.1%) with progression and 105 eyes (70.9%) without progression, according to Esterman's scale. In the group which showed progression, mean IOP (p less than 0.05), level of change in IOP and maximum of IOP (p less than 0.01) were significantly higher. No differences were observed in any of the following parameters: prevalence of peripapillary hemorrhage or crescent, rim pallor, disc/arteriole ratio, number of rim-crossing vessels. Mildly hypoplastic disc, however, was statistically more frequent in the progressive group (p less than 0.05). The authors suspect that not only IOP but some inherent factors concerning the optic nerve head may play an important role in the progression of LTG.
通过对74例诊断为低眼压性青光眼（LTG）患者的148只眼进行回顾性病例分析，研究了视盘外观与视野缺损进展之间的关系。采用Goldmann视野计检查视野，并根据Esterman标准将受试者分为两组，即进展组43只眼（29.1%）和非进展组105只眼（70.9%）。在进展组中，平均眼压（p<0.05）、眼压变化水平和最高眼压（p<0.01）显著更高。在以下任何参数中均未观察到差异：视盘周围出血或弧形斑的发生率、盘缘苍白、视盘/小动脉比值、盘缘交叉血管数量。然而，轻度发育不全的视盘在进展组中在统计学上更为常见（p<0.05）。作者怀疑，不仅眼压，而且一些与视神经乳头有关的内在因素可能在低眼压性青光眼的进展中起重要作用。
