Rhew Isaac C, Richardson Laura P, Lymp Jim, McTiernan Anne, McCauley Elizabeth, Stoep Ann Vander
Department of Epidemiology, University of Washington, Box 357236, Seattle, WA 98195, USA.
Gen Hosp Psychiatry. 2008 Sep-Oct;30(5):458-66. doi: 10.1016/j.genhosppsych.2008.06.008. Epub 2008 Jul 30.
The objectives of this study were to examine associations between depressive symptoms and body mass over 1 year during early adolescence and to assess how the associations might differ depending upon whether self-reported or directly measured height and weight were used.
Participants were 446 sixth-grade Seattle students. Depressive symptoms were assessed using the Mood and Feelings Questionnaire. Regression models were used to examine whether baseline depression status was associated with 12-month body mass index (BMI; using self-reported height and weight) and whether baseline overweight status was associated with 12-month depressive symptom score. Analyses were rerun among a subsample (n=165) who had height and weight directly measured.
Using BMI derived from self-reported values, depressed males had a significantly lower BMI than nondepressed males, while depressed females had a significantly higher BMI than nondepressed females, after adjusting for covariates. Among a subsample using measured height and weight values, however, depression was no longer associated with BMI in either gender. Baseline overweight status did not predict 12-month depression score.
Observed associations between depression and subsequent BMI were explained by differential misclassification of self-reported height and weight by depression status and gender. Direct measurement of height and weight may be necessary to ensure validity in studies of adolescent depression and weight-related outcomes.
本研究的目的是探讨青春期早期1年内抑郁症状与体重之间的关联,并评估根据使用的是自我报告的身高体重还是直接测量的身高体重,这些关联可能会有怎样的不同。
参与者为446名西雅图六年级学生。使用情绪与感受问卷评估抑郁症状。采用回归模型来检验基线抑郁状态是否与12个月时的体重指数(BMI;使用自我报告的身高和体重)相关,以及基线超重状态是否与12个月时的抑郁症状评分相关。在直接测量了身高和体重的子样本(n = 165)中重新进行分析。
使用自我报告值得出的BMI,在调整协变量后,抑郁男性的BMI显著低于非抑郁男性,而抑郁女性的BMI显著高于非抑郁女性。然而,在使用测量的身高和体重值的子样本中,抑郁与任何性别的BMI均不再相关。基线超重状态不能预测12个月时的抑郁评分。
抑郁与后续BMI之间观察到的关联是由抑郁状态和性别对自我报告的身高和体重的不同错误分类所解释的。在青少年抑郁和体重相关结局的研究中,可能需要直接测量身高和体重以确保有效性。