Angeles-Angeles A, Quintanilla-Martínez L, Larriva-Sahd J
Department of Pathology, Instituto Nacional de la Nutrición, Mexico City, Mexico.
Am J Clin Pathol. 1991 Sep;96(3):341-4. doi: 10.1093/ajcp/96.3.341.
A 39-year-old woman with a primary carcinoid of the common bile duct is presented. The tumor showed argyrophilia; and, by immunohistochemical studies, chromogranin, serotonin, and somatostatin were demonstrated. The patient has no symptoms 42 months after surgical treatment. To the authors' knowledge, this is the first report of a carcinoid of the common bile duct as studied by immunohistochemistry. When six choledochal carcinoids were reviewed, the following characteristics were observed: in none of the cases were endocrine symptoms present; women were affected more frequently than men; the carcinoids occurred in younger patients than did adenocarcinomas; metastases were present in half of the patients; and, as a group, carcinoids seemed to have a better prognosis than adenocarcinomas in this location.
本文报告一例39岁患有胆总管原发性类癌的女性患者。肿瘤显示嗜银性；免疫组化研究证实有嗜铬粒蛋白、5-羟色胺和生长抑素。该患者在手术治疗42个月后无症状。据作者所知，这是首例通过免疫组化研究胆总管类癌的报告。回顾6例胆总管类癌时，观察到以下特征：所有病例均无内分泌症状；女性比男性更易受累；类癌患者比腺癌患者年轻；半数患者有转移；总体而言，该部位类癌的预后似乎比腺癌更好。
