Saito Yoshio, Matsumoto Katsuhiko, Bag Subhendu Sekhar, Misawa Akihiro, Saito Isao
Department of Materials Chemistry and Engineering, and NEWCAT Institute, School of Engineering, Nihon University, Koriyama, Fukushima 963-8642, Japan.
Nucleic Acids Symp Ser (Oxf). 2008(52):357-8. doi: 10.1093/nass/nrn180.
C8-alkylamino substituted 2'-deoxyguanosine was incorporated into a DNA sequence and then labeled with pyrene. The conformational change from B- to Z-form was monitored using CD and fluorescence spectroscopy for both labeled and unlabeled ODNs.
将C8-烷基氨基取代的2'-脱氧鸟苷掺入DNA序列中，然后用芘进行标记。使用圆二色光谱（CD）和荧光光谱对标记和未标记的寡脱氧核苷酸（ODN）监测从B型到Z型的构象变化。
