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一名5个月大男婴的勒米尔综合征:病例报告及儿科文献综述

Lemierre syndrome in a 5-month-old male infant: Case report and review of the pediatric literature.

作者信息

Aspesberro François, Siebler Thomas, Van Nieuwenhuyse Jean-Paul, Panosetti Eugène, Berthet Françoise

机构信息

Divisions of Neonatal and Pediatric Intensive Care Unit (FA), Pediatric Radiology (JPVN), Otorhinolaryngology, Head and Neck Surgery (EP), and Pediatrics (FB), Clinique Pédiatrique, Centre Hospitalier de Luxembourg, Luxembourg, USA.

出版信息

Pediatr Crit Care Med. 2008 Sep;9(5):e35-7. doi: 10.1097/PCC.0b013e31817319fa.

Abstract

OBJECTIVES

To report, to the best of our knowledge, the youngest patient with Lemierre syndrome.

DESIGN

Descriptive case report with review of the pediatric literature.

SETTING

Pediatric intensive care unit in a tertiary referral hospital.

DATA SOURCE

Systemic review of the literature, including PubMed (English-only journals) and major textbooks.

PATIENT

We report a 5-month-old boy who presented with fever and a perforated left-sided otitis media. He developed left-sided complicated otitis media with retroauricular fluid collection, mastoiditis, and temporomandibular joint effusion. The clinical picture was complicated by a left internal jugular vein and left lateral sinus thrombosis. Fusobacterium necrophorum grew in the pus culture.

INTERVENTIONS

Low molecular weight heparin.

MEASUREMENTS AND MAIN RESULTS

No immunodeficiency and no thrombophilia were identified as predisposing conditions for Lemierre syndrome. Surgical drainage, early and adequate antibiotic treatment, and anticoagulation were followed by complete recovery.

CONCLUSIONS

This case report illustrates that Lemierre syndrome can occur in infants without underlying risk factors for severe infections or thrombotic complications.

摘要

目的

据我们所知,报告最年轻的勒米尔综合征患者。

设计

描述性病例报告并回顾儿科文献。

地点

一家三级转诊医院的儿科重症监护病房。

数据来源

对文献进行系统回顾,包括PubMed(仅英文期刊)和主要教科书。

患者

我们报告一名5个月大男孩,出现发热及左侧中耳炎穿孔。他发展为左侧复杂性中耳炎伴耳后积液、乳突炎及颞下颌关节积液。临床表现因左侧颈内静脉和左侧横窦血栓形成而复杂化。坏死梭杆菌在脓液培养中生长。

干预措施

低分子量肝素。

测量指标及主要结果

未发现免疫缺陷和易栓症作为勒米尔综合征的易感因素。手术引流、早期充分的抗生素治疗及抗凝治疗后完全康复。

结论

本病例报告表明,勒米尔综合征可发生于无严重感染或血栓形成并发症潜在危险因素的婴儿。

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