Suppr超能文献

椎体成形术治疗脊柱外疼痛性骨转移瘤:我们的经验

Cementoplasty in the management of painful extraspinal bone metastases: our experience.

作者信息

Basile A, Giuliano G, Scuderi V, Motta S, Crisafi R, Coppolino F, Mundo E, Banna G, Di Raimondo F, Patti M T

机构信息

Department of Diagnostic and Interventional Radiology, Ospedale Ferrarotto, Via Citelli 16, 95124 Catania, Italy.

出版信息

Radiol Med. 2008 Oct;113(7):1018-28. doi: 10.1007/s11547-008-0314-1. Epub 2008 Sep 8.

Abstract

PURPOSE

The aim of this study was to demonstrate the effectiveness of interventional techniques in the palliative management of painful extraspinal bone metastases.

MATERIALS AND METHODS

Cementoplasty alone or in combination with radiofrequency (RF) ablation was performed in 14 skeletal extravertebral segments in 13 patients with ages ranging from 50 to 74 (average 67) years. The primary tumours were myeloma (n=5), renal carcinoma (n=5), hepatocellular carcinoma (n=2) and bladder carcinoma (n=2). Metastases were located at the acetabulum (n=4), femur (n=5), humerus (n=1), scapula (n=2) and iliac bone (n=2). The clinical indication was a pain intensity score >4 on the visual analogue scale (VAS) partially or totally refractory to analgesic medication. Clinical evaluation was based on clinical and neurological conditions before and immediately after the procedure and during the follow-up.

RESULTS

Technical success was achieved in all cases. Ten patients were treated by cementoplasty alone and four cases by cementoplasty combined with RF ablation. After treatment, all patients experienced improved symptoms, as demonstrated by the VAS score, which remained constant during follow-up. All patients were followed for between 2 and 14 (average 6.1) months. We had one major complication in a patient who developed an abscess, which was treated by percutaneous drainage.

CONCLUSIONS

In our experience, cementoplasty alone for small lesions or combined with RF ablation in larger lesions is an effective and safe therapy in the palliative management of painful extraspinal bone metastases.

摘要

目的

本研究旨在证明介入技术在疼痛性脊柱外骨转移瘤姑息治疗中的有效性。

材料与方法

对13例年龄在50至74岁(平均67岁)的患者的14个脊柱外骨骼节段进行了单纯骨水泥成形术或联合射频(RF)消融术。原发肿瘤为骨髓瘤(n = 5)、肾癌(n = 5)、肝细胞癌(n = 2)和膀胱癌(n = 2)。转移灶位于髋臼(n = 4)、股骨(n = 5)、肱骨(n = 1)、肩胛骨(n = 2)和髂骨(n = 2)。临床指征为视觉模拟量表(VAS)疼痛强度评分>4,对止痛药物部分或完全无效。临床评估基于术前、术后即刻及随访期间的临床和神经状况。

结果

所有病例均取得技术成功。10例患者接受了单纯骨水泥成形术,4例患者接受了骨水泥成形术联合RF消融术。治疗后,所有患者症状均有改善,VAS评分显示了这一点,随访期间评分保持稳定。所有患者随访2至14个月(平均6.1个月)。1例患者出现脓肿这一主要并发症,经皮引流治疗。

结论

根据我们的经验,对于小病灶单纯骨水泥成形术或对于大病灶联合RF消融术,是疼痛性脊柱外骨转移瘤姑息治疗中一种有效且安全的治疗方法。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验