• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

射频消融和骨水泥成形术在增强骨盆恶性骨转移患者功能能力方面的疗效。

Effectiveness of RF ablation and cementoplasty in enhancing functional capacity in pelvic malignant bone metastases.

机构信息

Sincan Training and Research Hospital, Sincan, 06934, Ankara, Turkey.

Department of Orthopaedics and Traumatology, Faculty of Medicine, Hacettepe University, Altindag, 06230, Ankara, Turkey.

出版信息

Eur J Orthop Surg Traumatol. 2024 Oct;34(7):3609-3618. doi: 10.1007/s00590-024-04081-8. Epub 2024 Aug 21.

DOI:10.1007/s00590-024-04081-8
PMID:39167205
Abstract

PURPOSE

Pelvic and sacral bone metastases cause significant morbidity. The primary aim of the study is to thoroughly evaluate the increase in functional capacity resulting from combined RF ablation and cementoplasty surgery applied to malignant bone metastases of the pelvic bones.

METHODS

Twenty patients who underwent RF ablation and cementoplasty for malign pelvic bone and sacrum metastases between January 2014 and December 2021 were retrospectively identified. The inclusion criteria were having a life expectancy of more than 1 month, being > 18 years old, and having at least 1 month of follow-up. The Visual Anlogue Scale (VAS) pain, Karnofsky Performance Status (KP), and Musculoskelatal Tumor Society (MSTS) scores were calculated.

RESULTS

VAS pain values decreased, and KP values increased postoperatively (p = 0.006 and p = 0,013). There was no statistically significant increase in MSTS (p > 0.05). The correlation relationships between lesion filling ratio and VAS pain, KP, and MSTS scores were not statistically significant (p > 0.05). Cement leakage was observed in 5 patients (25.0%), and no symptoms related to this leakage were observed.

CONCLUSION

The pelvic region, given its close proximity to blood vessels, nerves, and joint areas, along with the distinct challenges associated with its surgery, requires separate evaluation. In studies evaluating applications in the isolated pelvic ring region, as in our study, functional gains have been most comprehensively assessed in this study, demonstrating that the procedure results in significant functional improvements.

摘要

目的

骨盆和骶骨转移导致明显的发病率。本研究的主要目的是全面评估 RF 消融联合骨水泥成形术治疗骨盆恶性骨转移后功能能力的提高。

方法

回顾性分析 2014 年 1 月至 2021 年 12 月间因骨盆和骶骨恶性转移而行 RF 消融联合骨水泥成形术的 20 例患者。纳入标准为预期寿命超过 1 个月,年龄大于 18 岁,随访至少 1 个月。计算视觉模拟评分(VAS)疼痛、卡诺夫斯基表现状态(KPS)和肌肉骨骼肿瘤学会(MSTS)评分。

结果

术后 VAS 疼痛值降低,KPS 值升高(p=0.006 和 p=0.013)。MSTS 无统计学显著增加(p>0.05)。病灶填充率与 VAS 疼痛、KPS 和 MSTS 评分之间无统计学显著相关性(p>0.05)。5 例(25.0%)患者发生骨水泥渗漏,但无相关症状。

结论

骨盆区域靠近血管、神经和关节区域,手术难度大,需要单独评估。在评估单独骨盆环区域应用的研究中,如本研究,该手术在功能增益方面得到了最全面的评估,证明该手术可显著改善功能。

相似文献

1
Effectiveness of RF ablation and cementoplasty in enhancing functional capacity in pelvic malignant bone metastases.射频消融和骨水泥成形术在增强骨盆恶性骨转移患者功能能力方面的疗效。
Eur J Orthop Surg Traumatol. 2024 Oct;34(7):3609-3618. doi: 10.1007/s00590-024-04081-8. Epub 2024 Aug 21.
2
Cementoplasty of pelvic bone metastases: systematic assessment of lesion filling and other factors that could affect the clinical outcomes.骨盆骨转移瘤的骨水泥成形术:对病变填充及其他可能影响临床结果的因素的系统评估。
Skeletal Radiol. 2019 Sep;48(9):1345-1355. doi: 10.1007/s00256-019-3156-0. Epub 2019 Feb 2.
3
Cementoplasty for managing painful bone metastases outside the spine.骨水泥成形术治疗脊柱外疼痛性骨转移。
Eur Radiol. 2014 Mar;24(3):731-7. doi: 10.1007/s00330-013-3071-z. Epub 2013 Nov 22.
4
The Hopeless Case? Palliative Cryoablation and Cementoplasty Procedures for Palliation of Large Pelvic Bone Metastases.无望病例?姑息性冷冻消融和骨水泥成形术治疗骨盆骨转移瘤。
Pain Physician. 2017 Nov;20(7):E1053-E1061.
5
Combination acetabular radiofrequency ablation and cementoplasty using a navigational radiofrequency ablation device and ultrahigh viscosity cement: technical note.使用导航射频消融设备和超高粘度骨水泥进行髋臼联合射频消融和骨水泥成形术:技术说明
Skeletal Radiol. 2016 Mar;45(3):401-5. doi: 10.1007/s00256-015-2263-9. Epub 2015 Sep 26.
6
Application of Percutaneous Osteoplasty in Treating Pelvic Bone Metastases: Efficacy and Safety.经皮骨成形术治疗骨盆骨转移瘤的疗效及安全性。
Cardiovasc Intervent Radiol. 2019 Dec;42(12):1738-1744. doi: 10.1007/s00270-019-02320-8. Epub 2019 Sep 23.
7
Navigation-guided percutaneous pelvic cementoplasty for metastatic bone pain: A case report.导航引导经皮骨盆骨水泥成形术治疗转移性骨痛:病例报告。
Medicine (Baltimore). 2021 Apr 16;100(15):e25521. doi: 10.1097/MD.0000000000025521.
8
Reinforced cementoplasty for pelvic tumour lesions and pelvic traumatic fractures: preliminary experience.骨水泥强化成形术治疗骨盆肿瘤病变和骨盆创伤性骨折:初步经验。
Eur Radiol. 2022 Sep;32(9):6187-6195. doi: 10.1007/s00330-022-08742-2. Epub 2022 Apr 1.
9
Radiofrequency ablation therapy combined with cementoplasty for painful bone metastases: initial experience.射频消融治疗联合骨水泥成形术治疗疼痛性骨转移瘤:初步经验
Cardiovasc Intervent Radiol. 2005 Sep-Oct;28(5):578-83. doi: 10.1007/s00270-004-0208-0.
10
Radiofrequency Ablation for the Palliative Treatment of Bone Metastases: Outcomes from the Multicenter OsteoCool Tumor Ablation Post-Market Study (OPuS One Study) in 100 Patients.射频消融治疗骨转移的姑息性治疗:多中心 OsteoCool 肿瘤消融后市场研究(OPuS One 研究)100 例患者的结果。
J Vasc Interv Radiol. 2020 Nov;31(11):1745-1752. doi: 10.1016/j.jvir.2020.07.014.

本文引用的文献

1
Percutaneous-Reinforced Osteoplasty: A Review of Emerging Treatment Strategies for Bone Interventions.经皮强化骨成形术:骨干预新兴治疗策略综述
J Clin Med. 2022 Sep 22;11(19):5572. doi: 10.3390/jcm11195572.
2
Interventional Radiology in the Management of Metastases and Bone Tumors.介入放射学在转移瘤和骨肿瘤治疗中的应用
J Clin Med. 2022 Jun 7;11(12):3265. doi: 10.3390/jcm11123265.
3
Combination of Percutaneous Screw Fixation and Cementoplasty for Lytic Bone Metastases: Feasibility, Safety and Clinical Outcomes.经皮螺钉固定联合骨水泥成形术治疗溶骨性骨转移瘤:可行性、安全性和临床疗效。
Cardiovasc Intervent Radiol. 2022 Aug;45(8):1129-1133. doi: 10.1007/s00270-022-03186-z. Epub 2022 Jun 21.
4
CIRSE Standards of Practice on Thermal Ablation of Bone Tumours.CIRSE 骨肿瘤热消融治疗实践标准。
Cardiovasc Intervent Radiol. 2022 May;45(5):591-605. doi: 10.1007/s00270-022-03126-x. Epub 2022 Mar 29.
5
Bipolar Radiofrequency Ablation of Painful Spinal Bone Metastases Performed under Local Anesthesia: Feasibility Regarding Patient's Experience and Pain Outcome.局部麻醉下脊柱骨转移痛的双极射频消融术:患者体验和疼痛转归的可行性。
Medicina (Kaunas). 2021 Sep 15;57(9):966. doi: 10.3390/medicina57090966.
6
Image-guided Percutaneous Fixation with Internal Cemented Screws of Impending Femoral Neck Pathologic Fractures in Patients with Metastatic Cancer: Safety, Efficacy, and Durability.影像引导下经皮置入带水泥螺钉治疗转移性骨肿瘤股骨颈病理性骨折:安全性、疗效及持久性。
Radiology. 2020 Dec;297(3):721-729. doi: 10.1148/radiol.2020201341. Epub 2020 Oct 6.
7
Effectiveness of Radiofrequency Ablation in the Treatment of Painful Osseous Metastases: A Correlation Meta-Analysis with Machine Learning Cluster Identification.射频消融治疗骨转移疼痛的疗效:基于机器学习聚类识别的相关性荟萃分析。
J Vasc Interv Radiol. 2020 Nov;31(11):1753-1762. doi: 10.1016/j.jvir.2020.08.002. Epub 2020 Oct 1.
8
Interventional radiology for treatment of bone metastases.介入放射学治疗骨转移瘤
Cancer Radiother. 2020 Aug;24(5):374-378. doi: 10.1016/j.canrad.2020.04.006. Epub 2020 Jun 8.
9
Minimally Invasive Image-Guided Ablation, Osteoplasty, Reinforcement, and Internal Fixation (AORIF) for Osteolytic Lesions in the Pelvis and Periarticular Regions of Weight-Bearing Bones.微创影像引导下消融、整形、强化和内固定(AORIF)治疗承重骨骨盆和关节周围区域溶骨性病变。
J Vasc Interv Radiol. 2020 Apr;31(4):649-658.e1. doi: 10.1016/j.jvir.2019.11.029. Epub 2020 Mar 3.
10
Percutaneous extra-spinal cementoplasty in patients with cancer: A systematic review of procedural details and clinical outcomes.经皮椎管外骨水泥成形术治疗癌症患者:手术细节和临床结局的系统评价。
Diagn Interv Imaging. 2019 Dec;100(12):743-752. doi: 10.1016/j.diii.2019.07.005. Epub 2019 Aug 16.