Ni Rui-Fang, Kranokpiraksa Pawanrat, Pavcnik Dusan, Kakizawa Hideaki, Uchida Barry T, Keller Frederick S, Rösch Josef
Dotter Interventional Institute, Oregon Health Sciences University, Portland, OR 97201, USA.
Cardiovasc Intervent Radiol. 2009 Mar;32(2):313-6. doi: 10.1007/s00270-008-9426-1. Epub 2008 Sep 9.
The ovine superficial femoral artery was used for testing the efficacy of percutaneous arterial closure devices (PACDs) in their developmental stage. Two topical devices containing chitostan, one staple-mediated PACD and a porcine small intestinal submucosa plug, were tested by follow-up angiography in 37 sheep. Absence or presence of bleeding and time to bleeding cessation were the main criteria for evaluation of PAVD efficacy. The results of these tests directed modification of individual PACDs and improved their efficacy.
