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磷脂酶A2——炎症近端和远端效应器之间的介质。

Phospholipase A2--a mediator between proximal and distal effectors of inflammation.

作者信息

Pruzanski W, Vadas P

机构信息

University of Toronto, Canada.

出版信息

Immunol Today. 1991 May;12(5):143-6. doi: 10.1016/S0167-5699(05)80042-8.

DOI:10.1016/S0167-5699(05)80042-8
PMID:1878124
Abstract

Phospholipase A2 (PLA2) is known to play an important intracellular role in inflammatory processes but does it also perform a vital function extracellularly? Here, W. Pruzanski and P. Vadas marshall the evidence supporting PLA2 as a mediator of inflammation, specifically in linking local and systemic effects.

摘要

已知磷脂酶A2（PLA2）在炎症过程中发挥重要的细胞内作用，但它在细胞外是否也起着至关重要的作用呢？在此，W.普鲁赞斯基和P.瓦达斯汇集了支持PLA2作为炎症介质的证据，特别是在将局部和全身效应联系起来方面。

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