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共生型阴囊平滑肌瘤:一例报告

Symplastic scrotal leiomyoma: a case report.

作者信息

Philip Joe, Manikandan Ramaswamy, Vishwanathan Palaniswamy, Mathew Joseph

机构信息

Department of Urology, Royal Cornwall Hospital, Truro, UK.

出版信息

J Med Case Rep. 2008 Sep 9;2:295. doi: 10.1186/1752-1947-2-295.

Abstract

INTRODUCTION

Scrotal leiomyomas are rare tumours which are essentially benign. Recurrence and malignant transformation to leiomyosarcoma have been reported. However, a specific subgroup with increased bizarre nuclei showing increased mitosis raises the need for a closer follow-up. We report on such a case.

CASE PRESENTATION

We report the case of a 65-year-old man who underwent a scrotal lump excision. Histology showed a well defined leiomyoma. The presence of nuclear pleomorphism and mitoses, just falling short of the criteria for malignancy, made prediction of biological behaviour difficult. The patient remains well on 4-year follow-up.

CONCLUSION

Histological evidence of increased mitosis raises the need for sustained follow-up in view of the malignant potential from the extent of mitosis. Immunohistochemistry helps in identifying those patients warranting close follow-up.

摘要

引言

阴囊平滑肌瘤是一种罕见的肿瘤,本质上为良性。已有复发及恶变至平滑肌肉瘤的相关报道。然而,存在一个具有增多的奇异核且有丝分裂增加的特定亚组,这就需要更密切的随访。我们报告这样一例病例。

病例介绍

我们报告一名65岁男性阴囊肿块切除病例。组织学检查显示为边界清晰的平滑肌瘤。存在核异形性和有丝分裂,但未达到恶性标准,这使得生物学行为的预测变得困难。该患者在4年随访期内情况良好。

结论

鉴于有丝分裂程度所提示的恶性潜能,有丝分裂增加的组织学证据表明需要持续随访。免疫组化有助于识别那些需要密切随访的患者。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9236/2542396/2d971ed76298/1752-1947-2-295-1.jpg

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