原发性干燥综合征伴肿胀性中枢神经系统受累。
Primary Sjögren Syndrome with tumefactive central nervous system involvement.
作者信息
Sanahuja J, Ordoñez-Palau S, Begué R, Brieva L, Boquet D
机构信息
Department of Neurology, Hospital Universitari Arnau de Vilanova-IRBLleida, Lleida, Spain.
出版信息
AJNR Am J Neuroradiol. 2008 Nov;29(10):1878-9. doi: 10.3174/ajnr.A1204. Epub 2008 Sep 10.
Abstract
Brain MR imaging abnormalities in primary Sjögren syndrome (pSS) are generally discrete white matter lesions. We describe a 50-year-old woman with recurrent neurologic deficits. MR imaging revealed a large brain lesion. A diagnosis of pSS was made on the basis of clinical features, positive anti-Ro and anti-La antibodies, abnormal Schirmer test findings, and salivary gland scintigraphy. The patient was treated with oral prednisone with good response. Large tumefactive brain lesions are a complication of pSS.
摘要
原发性干燥综合征（pSS）的脑部磁共振成像异常通常为散在的白质病变。我们描述了一名50岁复发性神经功能缺损的女性。磁共振成像显示一个大的脑部病变。根据临床特征、抗Ro和抗La抗体阳性、泪液分泌试验结果异常以及唾液腺闪烁扫描，诊断为pSS。该患者接受口服泼尼松治疗，反应良好。巨大肿块性脑部病变是pSS的一种并发症。
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本文引用的文献
1
Relapsing-remitting tumefactive multiple sclerosis.
Mult Scler. 2005 Dec;11(6):731-4. doi: 10.1191/1352458505ms1214cr.
2
[Neurological manifestations in Sjögren syndrome].
Rev Med Interne. 2005 Aug;26(8):624-36. doi: 10.1016/j.revmed.2005.02.014. Epub 2005 Apr 8.
3
Multiple sclerosis: pseudotumoral forms.
Neurol Sci. 2004 Nov;25 Suppl 4:S374-9. doi: 10.1007/s10072-004-0345-x.
4
Central nervous system disease in primary Sjogrens syndrome: the role of magnetic resonance imaging.
Semin Arthritis Rheum. 2004 Dec;34(3):623-30. doi: 10.1016/j.semarthrit.2004.07.005.
5
Neurologic manifestations in primary Sjögren syndrome: a study of 82 patients.
Medicine (Baltimore). 2004 Sep;83(5):280-291. doi: 10.1097/01.md.0000141099.53742.16.
6
Central nervous system involvement in Sjogren's syndrome.
Ann Rheum Dis. 2004 Jun;63(6):616-20. doi: 10.1136/ard.2003.019497.
7
Primary Sjögren syndrome: clinical and immunologic disease patterns in a cohort of 400 patients.
Medicine (Baltimore). 2002 Jul;81(4):270-80. doi: 10.1097/00005792-200207000-00003.
8
Tumefactive multiple sclerosis plaque.
J Neurol Neurosurg Psychiatry. 2002 Jul;73(1):85. doi: 10.1136/jnnp.73.1.85.
9
Classification criteria for Sjögren's syndrome: a revised version of the European criteria proposed by the American-European Consensus Group.
Ann Rheum Dis. 2002 Jun;61(6):554-8. doi: 10.1136/ard.61.6.554.
10
Pseudolymphoma of the liver associated with Sjögren's syndrome.
Scand J Rheumatol. 2001;30(2):117-9. doi: 10.1080/03009740151095466.
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