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婴幼儿主动脉缩窄合并心内畸形的外科治疗

[Surgical treatment of aortic coarctation with intracardiac anomaly in infants and toddlers].

作者信息

Yu Qi-Bin, Shen Xiang-Dong, Li Shou-Jun, Hua Zhong-Dong, Liu Jin-Ping, Liu Ying-Long, Hu Sheng-Shou

机构信息

Pediatric Center, Fuwai Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing 100037, China.

出版信息

Zhonghua Wai Ke Za Zhi. 2008 Apr 1;46(7):528-30.

Abstract

OBJECTIVE

To review the experience in repair of aortic coarctation with intracardiac anomaly in infants and toddlers.

METHODS

From January 2000 to December 2006, 84 infants and children diagnosed as aortic coarctation with intracardiac anomaly underwent surgical treatment. Mean age of the patients was 13.5 months, with a range from 1 month to 3 years. Mean body weight was 7.3 kg, with a range from 3.3 to 15 kg. Twelve patients complicated with complex intracardiac anomaly. Seventy-two patients complicated with ventricular septal defect and other simple anomaly. Twenty-one patients had hypoplasia of the aortic arch. Sixty-two patients had one-stage repair. Median sternotomy was used to simultaneously repair coarctation and intracardiac defect in 49 patients. Left thoracotomy and median sternotomy were applied to repair aortic coarctation and intracardiac anomaly respectively in 13 patients. Twenty-two patients had staged repair. Operational techniques for aortic coarctation include 42 patients of patch aortoplasty, 30 patients of resection and end-to-end anastomosis, 6 patients of subclavian flap aortoplasty, 3 patients of vascular bypass, and 1 patient of balloon dilation. In all 49 patients of one-stage operation through median sternotomy, selective cerebral perfusion was used in 43 patients, deep hypothermia low flow was applied in 4 patients, deep hypothermia circulatory arrest was performed in 2 patients.

RESULTS

There were 8 hospital deaths. The mortality is 9.5%. Among 8 deaths, 3 patients were misdiagnosed.

CONCLUSIONS

Surgeries for aortic coarctation with intracardiac anomaly have satisfactory short-term results in infants and toddlers. One-stage repair through median sternotomy can be applied to most of the patients. Selective cerebral perfusion with deep hypothermia and circulatory arrest in lower body can protect the brain and other vital organs.

摘要

目的

回顾婴幼儿主动脉缩窄合并心内畸形的修复经验。

方法

2000年1月至2006年12月,84例诊断为主动脉缩窄合并心内畸形的婴幼儿接受了手术治疗。患者平均年龄13.5个月,范围为1个月至3岁。平均体重7.3kg,范围为3.3至15kg。12例患者合并复杂心内畸形。72例患者合并室间隔缺损及其他简单畸形。21例患者存在主动脉弓发育不良。62例患者接受一期修复。49例患者采用正中胸骨切开术同时修复缩窄和心内缺损。13例患者分别采用左胸切口和正中胸骨切开术修复主动脉缩窄和心内畸形。22例患者接受分期修复。主动脉缩窄的手术技术包括42例补片主动脉成形术、30例切除端端吻合术、6例锁骨下皮瓣主动脉成形术、3例血管旁路术和1例球囊扩张术。在所有49例通过正中胸骨切开术进行一期手术的患者中,43例采用选择性脑灌注,4例采用深低温低流量,2例采用深低温循环停止。

结果

有8例住院死亡。死亡率为9.5%。在8例死亡中,3例患者被误诊。

结论

婴幼儿主动脉缩窄合并心内畸形的手术短期效果满意。大多数患者可采用正中胸骨切开术一期修复。深低温下半身循环停止并选择性脑灌注可保护脑和其他重要器官。

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