高压氧疗法治疗动静脉畸形立体定向放射外科术后的放射性不良反应：病例报告及文献复习
Hyperbaric oxygen therapy for treatment of adverse radiation effects after stereotactic radiosurgery of arteriovenous malformations: case report and review of literature.
作者信息
Wanebo John E, Kidd Grant A, King Michael C, Chung Thomas S
机构信息
Department of Neurosciences, Naval Medical Center San Diego, San Diego, CA, USA.
出版信息
Surg Neurol. 2009 Aug;72(2):162-7; discussion 167-8. doi: 10.1016/j.surneu.2008.03.037. Epub 2008 Sep 11.
BACKGROUND
Adverse radiation effects are a known complication after the use of SRS for AVMs, although it is difficult to predict which patients will manifest with these side effects. Treatment of swelling due to ARE is usually medical, but refractory cases may require surgical decompression.
CASE DESCRIPTION
This report presents a case of a patient who experienced AREs after SRS (edema, headaches, and nausea) that failed to respond to steroid treatment but was successfully treated with HBO. The treatment characteristics of this and of 5 other cases of radiation injury after SRS for AVM managed with HBO therapy are reviewed, and the pathophysiology is discussed.
CONCLUSION
Hyperbaric oxygen therapy provides a therapeutic option to treat AREs following SRS of cerebral AVMs.
背景
尽管难以预测哪些患者会出现这些副作用，但使用立体定向放射外科（SRS）治疗动静脉畸形（AVM）后，辐射不良反应是一种已知的并发症。放射性水肿的治疗通常采用药物治疗，但难治性病例可能需要手术减压。
病例描述
本报告介绍了一名患者，该患者在接受SRS治疗后出现了放射性不良反应（水肿、头痛和恶心），对类固醇治疗无反应，但通过高压氧（HBO）治疗成功治愈。本文回顾了该病例以及其他5例接受HBO治疗的SRS治疗AVM后放射性损伤病例的治疗特点，并讨论了其病理生理学。
结论
高压氧疗法为治疗脑AVM的SRS术后放射性不良反应提供了一种治疗选择。
Zotero 插件