高压氧疗法治疗放射性黄斑缺血
Hyperbaric oxygen therapy for the treatment of radiation-induced macular ischemia.
作者信息
Haji Shamim A, Frenkel Ronald Ep
机构信息
Eye Research Foundation, Stuart, FL, USA.
出版信息
Clin Ophthalmol. 2010 May 14;4:433-6. doi: 10.2147/opth.s9803.
PURPOSE
To report a case of radiation-induced macular ischemia where vision and macular perfusion improved after hyperbaric oxygen (HBO) therapy.
METHODS
A 62-year-old male patient developed radiation-induced macular ischemia after he was treated with radiation for brain glioma. The patient presented with best spectacle-corrected visual acuity (BSCVA) acuity of 20/400 in his right eye. Optical coherence tomography (OCT) showed central macular thickness of 468 mum. The patient received focal laser, intravitreal triamcinolone, and HBO therapy.
RESULTS
The patient's vision improved from 20/400 to 20/100 after focal laser and intravitreal triamcinolone. His central macular thickness improved from 468 mum to 132 mum. After receiving HBO therapy, his VA improved to 20/50 and fluorescein angiography showed improvement in macular perfusion.
CONCLUSION
HBO therapy improves macular perfusion in patients with radiation-induced macular ischemia.
目的
报告一例放射性黄斑缺血病例，该患者在接受高压氧（HBO）治疗后视力和黄斑灌注得到改善。
方法
一名62岁男性患者在接受脑胶质瘤放射治疗后发生放射性黄斑缺血。患者右眼最佳矫正视力（BSCVA）为20/400。光学相干断层扫描（OCT）显示中心黄斑厚度为468μm。患者接受了局部激光、玻璃体内注射曲安奈德和HBO治疗。
结果
在接受局部激光和玻璃体内注射曲安奈德治疗后，患者视力从20/400提高到20/100。其中心黄斑厚度从468μm改善至132μm。接受HBO治疗后，其视力提高到20/50，荧光素血管造影显示黄斑灌注有所改善。
结论
HBO治疗可改善放射性黄斑缺血患者的黄斑灌注。
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