Martínez Jorge V, Verbanaz Sergio C, Jordán Rosana, Enríquez Natalia, Efrón Ernesto D
Servicio de Infectología. Hospital Británico, Buenos Aires, Argentina.
Medicina (B Aires). 2008;68(4):298-300.
Chronic meningococcemia is an unfrequent clinical picture within the spectrum of infections produced by Neisseria meningitidis. It is classically characterized by fever, skin lesions and joint involvement, usually without meningeal involvement, and with blood culture growth of the responsible bacteria. It generally affects previously healthy young people. It is unknown why these patients, unlike patients with Neisseria meningitidis's acute meningitis and with acute meningococcemia, can survive without complications during weeks, in abscence of an useful antibiotic treatment. It has been hypothesized that owing to high susceptibility to beta-lactam antibiotics of Neisseria meningitidis, many cases may be treated inadvertently. We describe a case of chronic meningococcemia in a young woman who presented a classical clinical picture, not recognized initially.
慢性脑膜炎球菌血症是脑膜炎奈瑟菌引起的感染范围内一种不常见的临床表现。其典型特征为发热、皮肤病变和关节受累,通常无脑膜受累,且血培养可培养出致病细菌。它一般影响既往健康的年轻人。目前尚不清楚为何这些患者与患急性脑膜炎球菌性脑膜炎和急性脑膜炎球菌血症的患者不同,在没有有效的抗生素治疗的情况下,数周内仍能无并发症地存活。据推测,由于脑膜炎奈瑟菌对β-内酰胺类抗生素高度敏感,许多病例可能得到了无意的治疗。我们描述了一名年轻女性慢性脑膜炎球菌血症的病例,该患者呈现出典型的临床表现,但最初未被识别。