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以急性多关节炎为表现的脑膜炎球菌血症。

Meningococcemia presenting as acute polyarthritis.

作者信息

Pinals R S

出版信息

J Rheumatol. 1977 Winter;4(4):420-4.

PMID:415140
Abstract

Four patientw with acute polyarthritis due to meningcoccemia are described. One had skin manifestations suggesting vasculitis, another had transient nodular lesions, but there were none of these features in the other two. Synovial fluid cultures were negative and cells counts did not suggest septic arthritis. The diagnosis was not suspected until positive blood cultures were reported in three cases and meningitis developed in the fourth. In spite of diagnostic delay due to slow growth in cultures (six to 11 days) there was prompt response to antibiotic treatment. Meningococcemia should be suspected in patients presenting with fever and polyarthritis, even in the absence of skin lesions.

摘要

本文描述了4例因脑膜炎球菌血症导致急性多关节炎的患者。1例有提示血管炎的皮肤表现,另1例有短暂的结节性病变,但另外2例没有这些特征。滑膜液培养为阴性,细胞计数也不提示为化脓性关节炎。在3例血培养呈阳性且第4例发生脑膜炎之前,均未怀疑有该诊断。尽管由于培养生长缓慢(6至11天)导致诊断延迟,但抗生素治疗仍有迅速反应。对于出现发热和多关节炎的患者,即使没有皮肤病变,也应怀疑有脑膜炎球菌血症。

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