Suttorp M, Schmitz N, Prange E, Ganser A, Löffler H, Schaub J
Dept. of Pediatrics, Univ. of Kiel, FRG.
Bone Marrow Transplant. 1991;7 Suppl 2:84.
We report the case of a boy with juvenile chronic myeloid leukemia (jCML), who after initial treatment with interferon alpha-2 (IFN) and hydroxyurea underwent bone marrow transplantation (BMT) from a matched unrelated donor complicated by graft failure. Subsequent stimulation of hematopoiesis by GM-CSF and IL-3 promoted autologous recovery. In contrast to the course of disease pre-BMT, the boy is now off any therapy remaining in complete remission more than 500 days after BMT.
我们报告了一名患有青少年慢性髓性白血病（jCML）的男孩的病例，该男孩在先用α-2干扰素（IFN）和羟基脲进行初始治疗后，接受了来自匹配无关供者的骨髓移植（BMT），但并发了移植物失败。随后用粒细胞-巨噬细胞集落刺激因子（GM-CSF）和白细胞介素-3（IL-3）刺激造血促进了自体恢复。与BMT前的病程不同，该男孩现在已停止任何治疗，在BMT后500多天仍处于完全缓解状态。
