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[关节软骨损伤的治疗]

[Therapy of articular cartilage lesions].

作者信息

Albrecht D, Weise K

机构信息

Sektion arthroskopische Chirurgie und Sporttraumatologie, Berufsgenossenschaftliche Unfallklinik, Schnarrenbergstrasse 95, 72076, Tübingen, Deutschland.

出版信息

Chirurg. 2008 Oct;79(10):989-98; quiuz 999-1000. doi: 10.1007/s00104-008-1600-0.

DOI:10.1007/s00104-008-1600-0
PMID:18787803
Abstract

Lesions of adult articular cartilage do not heal or regenerate. They give rise to the development of osteoarthritis, and surgical treatment is necessary before the initiation of joint degeneration. Various treatment modalities ranging from microfracture to autologous mosaicplasty and autologous chondrocyte transplantation are available. Commonly they are distinguished by the presence or absence of cell transplantation. The treatment choice depends on size, depth, and location of the lesion; therefore exact classification is mandatory. The surgical procedure aims to reconstruct a physiological distribution of the biomechanical forces by surface restoration. Additional joint pathologies such as mechanical axis deviation, meniscal defects, and ligament insufficiencies threaten the surgical success and must be addressed simultaneously.

摘要

成人关节软骨损伤不会自行愈合或再生。它们会引发骨关节炎,因此在关节开始退变之前进行手术治疗是必要的。从微骨折到自体镶嵌成形术和自体软骨细胞移植等各种治疗方式都有。通常它们根据是否存在细胞移植来区分。治疗方案的选择取决于损伤的大小、深度和位置;因此精确分类是必不可少的。手术过程旨在通过表面修复重建生物力学力的生理分布。其他关节病变,如机械轴偏差、半月板缺损和韧带功能不全,会威胁手术的成功,必须同时加以解决。

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本文引用的文献

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