Chen S Y, Liu H T, Ho J C
Department of Dermatology, Chang Gung Memorial Hospital, Kaohsiung, Taiwan, R.O.C.
Changgeng Yi Xue Za Zhi. 1991 Jun;14(2):106-10.
Twenty-two patients with pilomatricoma seen from January 1986 to October 1990 were analyzed retrospectively. The incidence of pilomatricoma in our dermatopathologic material is 1 in every 50 cases of skin tumors. Male to female ratio is 1:2. Half of the tumors appeared before the age of 30. Most of the tumors develop in the head, neck and upper extremities. Two pilomatricomas appeared with overlying bullae. Pathologically, multiple dilated lymphatics in the dermis were found above the typical nests of shadow cells and basophilic cells. Clues to clinical diagnosis are summarized below. The stony hard, deep-seated tumor, covered by normal skin, is usually located in the upper extremity. Tumors with blue-red discoloration, firm or elastic, frequently found in eyelid and face, are located more superficially, clinically they should be differentiated from epidermal cysts. Erythematous protruding tumors occur in the scalp or face. Bullous pilomatricoma is characteristically manifested as a flaccid, thick-walled bulla with an underlying palpable hard nodule, usually seen in the shoulder, upper arm or the head.
对1986年1月至1990年10月间收治的22例毛发瘤患者进行回顾性分析。在我们的皮肤病理材料中，毛发瘤的发病率为每50例皮肤肿瘤中有1例。男女比例为1:2。半数肿瘤出现在30岁之前。大多数肿瘤发生在头、颈和上肢。有2例毛发瘤伴有上方大疱。病理检查发现，在典型的影细胞和嗜碱性细胞巢上方的真皮中有多个扩张的淋巴管。临床诊断线索总结如下。质地坚硬如石、位于深部、表面覆盖正常皮肤的肿瘤，通常位于上肢。呈蓝红色、质地硬或有弹性的肿瘤，常见于眼睑和面部，位置较浅，临床上应与表皮囊肿相鉴别。头皮或面部出现红斑性突出肿瘤。大疱性毛发瘤的特征表现为松弛、厚壁的大疱，其下可触及坚硬结节，常见于肩部、上臂或头部。
