Belliappa Pr, Umashankar N, Raveendra Leena
Department of Dermatology, Rajarajeswari Medical College and Hospital, Kambipura, Kengeri Hobli, Bangalore, Karnataka, India.
Int J Trichology. 2013 Jan;5(1):32-4. doi: 10.4103/0974-7753.114716.
Pilomatricoma (pilomatrixoma) or calcifying epithelioma of Malherbe, is a tumor with differentiation toward hair cells, particularly hair cortex cells. It frequently presents as a firm, deep-seated nodule that is covered by normal skin. Bullous pilomatricoma is an unusual clinical variant. Reports on bullous variant of pilomatricoma is sparse, and only 17 cases have been reported world-wide until date out of which only two cases are reported from India. We present a report of a 17-year-old female with a solitary reddish semi-transparent blister over her right upper arm since 3 months resembling a bouncy ball. Histopathology revealed tumor nests of basophilic cells and eosinophilic shadow cells, which are consistent with pilomatricoma.
毛母质瘤(毛发基质瘤)或马尔赫布钙化上皮瘤,是一种向毛细胞尤其是毛皮质细胞分化的肿瘤。它常表现为一个坚实的、位于深部的结节,表面覆盖着正常皮肤。大疱性毛母质瘤是一种不寻常的临床变异型。关于大疱性毛母质瘤的报道稀少,截至目前全球仅报道了17例,其中印度仅报道了2例。我们报告一例17岁女性,右上臂出现一个孤立的红色半透明水疱,持续3个月,类似弹力球。组织病理学显示嗜碱性细胞和嗜酸性影细胞的肿瘤巢,符合毛母质瘤表现。