Malhotra Amit Kumar, Gupta Somesh, Khaitan Binod K, Verma Kaushal K
Department of Dermatology and Venereology, All India Institute of Medical Sciences, New Delhi, India.
Pediatr Dermatol. 2008 Jul-Aug;25(4):488-91. doi: 10.1111/j.1525-1470.2008.00727.x.
We report successful treatment of multiple basal cell carcinomas with imiquimod 5% cream in a 16-year-old boy with xeroderma pigmentosum and review the possibility of prophylactic role of imiquimod in the disease. Imiquimod cream was applied uniformly over all the basal cell carcinoma lesions and background pigmented skin, once at bedtime on every alternate day for 12 weeks. Besides the basal cell carcinomas, the background hyperpigmentation and keratotic papules also cleared, and the skin texture improved. The lesions did not recur at the treated sites during the follow up of 1 year.
我们报告了一名患有着色性干皮病的16岁男孩使用5%咪喹莫特乳膏成功治疗多发性基底细胞癌的病例，并探讨了咪喹莫特在该疾病中的预防作用。将咪喹莫特乳膏均匀涂抹于所有基底细胞癌病灶及周围色素沉着皮肤，每隔一天在睡前涂抹一次，持续12周。除基底细胞癌外，周围的色素沉着和角化丘疹也消退了，皮肤质地得到改善。在1年的随访中，治疗部位的病灶未复发。
