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非综合征性多发性基底细胞癌

Nonsyndromic Multiple Basal Cell Carcinomas.

作者信息

Kim Dong Hwi, Ko Hyo Sun, Jun Young Joon

机构信息

Department of Plastic and Reconstructive Surgery, Bucheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.

出版信息

Arch Craniofac Surg. 2017 Sep;18(3):191-196. doi: 10.7181/acfs.2017.18.3.191. Epub 2017 Sep 26.

DOI:10.7181/acfs.2017.18.3.191
PMID:29090201
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5647844/
Abstract

Basal cell carcinoma (BCC) comprising several lesions is not uncommon, but nonsyndromic multiple BCCs with parotid invasion are rare entities. We present two cases of multiple sporadic, nonsyndromic BCCs, and one of these cases is a unique case of parotid invasion associated purely with actinic keratosis. In Case 1, a 79-year-old female presented with multiple skin lesions on the face and left hand. All lesions were completely removed by surgery. The pathologic results showed lesions consistent with BCC and some lesions consistent with actinic keratosis. After 8 months, the patient presented with skin lesions in bilateral temporal areas and left cheek area. Surgical excision of the lesions was performed, and the biopsy results were squamous cell carcinoma in situ and actinic keratosis. In Case 2, a 43-year-old woman presented with multiple skin lesions on the face, scalp, right chest, abdomen and right leg. All lesions were completely removed by surgery. Pathologic evaluation confirmed the diagnosis of BCC. BCC is rarely metastatic, but it can lead to severe disfiguration or destruction. It is important to diagnose and treat BCC at an early stage.

摘要

包含多个病灶的基底细胞癌(BCC)并不少见,但非综合征性多发性BCC伴腮腺侵犯则较为罕见。我们报告两例多发性散发性、非综合征性BCC病例,其中一例是单纯与光化性角化病相关的腮腺侵犯的独特病例。病例1中,一名79岁女性面部和左手出现多个皮肤病变。所有病变均通过手术完全切除。病理结果显示病变符合BCC,部分病变符合光化性角化病。8个月后,患者双侧颞部和左颊部出现皮肤病变。对病变进行了手术切除,活检结果为原位鳞状细胞癌和光化性角化病。病例2中,一名43岁女性面部、头皮、右胸、腹部和右腿出现多个皮肤病变。所有病变均通过手术完全切除。病理评估确诊为BCC。BCC很少发生转移,但可导致严重的毁容或组织破坏。早期诊断和治疗BCC很重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b39/5647844/bff74ba41ae8/acfs-18-191-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b39/5647844/e4e9ab8ef7ce/acfs-18-191-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b39/5647844/4f6621bab729/acfs-18-191-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b39/5647844/b6a7af1d9e96/acfs-18-191-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b39/5647844/09235d4baa92/acfs-18-191-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b39/5647844/bff74ba41ae8/acfs-18-191-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b39/5647844/e4e9ab8ef7ce/acfs-18-191-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b39/5647844/4f6621bab729/acfs-18-191-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b39/5647844/b6a7af1d9e96/acfs-18-191-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b39/5647844/09235d4baa92/acfs-18-191-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b39/5647844/bff74ba41ae8/acfs-18-191-g005.jpg

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