Liu Z
Institute of Respiratory Diseases, China Medical University.
Zhonghua Jie He He Hu Xi Za Zhi. 1991 Apr;14(2):83-5, 126-7.
Doppler echocardiography and right heart catheterization were performed in 18 patients with COPD. The pulmonary blood flow pattern were analysed by the pulsed doppler flowmeter. The pulmonary artery acceleration time (PAT) showed significant inverse correlation with pulmonary artery mean pressure (mPAP) (r = -0.84, P less than 0.001) and pulmonary artery systolic pressure (sPAP) (r = -0.89, P less than 0.001). In fifteen of 18 patients, continuous wave doppler could be used to measure the maximal velocity of the regurgitant jet through the tricuspid valve (Vmax), and the right ventricle to the right atrium pressure gradient (PG) was calculated by means of simplified bernoulli equation (PG = 4V2max). PG correlated well with sPAP (r = 0.89, P less than 0.001) and mPAP (r = 0.92, P less than 0.001). We considered that doppler echocardiography was useful for noninvasive estimation of pulmonary artery pressure in patients with COPD.
对18例慢性阻塞性肺疾病（COPD）患者进行了多普勒超声心动图检查和右心导管检查。采用脉冲多普勒流量计分析肺血流模式。肺动脉加速时间（PAT）与肺动脉平均压（mPAP）呈显著负相关（r = -0.84，P < 0.001），与肺动脉收缩压（sPAP）呈显著负相关（r = -0.89，P < 0.001）。在18例患者中的15例中，可使用连续波多普勒测量经三尖瓣反流束的最大速度（Vmax），并通过简化伯努利方程计算右心室与右心房压力阶差（PG）（PG = 4V2max）。PG与sPAP（r = 0.89，P < 0.001）和mPAP（r = 0.92，P < 0.001）相关性良好。我们认为多普勒超声心动图对COPD患者肺动脉压力的无创评估有用。
