Hoskins J D, Bunge M M, Dubey J P, Duncan D E
Department of Veterinary Clinical Sciences, School of Veterinary Medicine, Louisiana State University, Baton Rouge 70803.
Cornell Vet. 1991 Jul;81(3):329-34.
Naturally-occurring neosporosis with multiple organ involvement was identified in a 10-year-old neutered male Basset hound dog. Clinical signs were first noticed 3 weeks prior to referral and consisted of crouched stance and mild pelvic limb ataxia. Dexamethasone administration had provided transient improvement. On presentation to the teaching hospital, clinical signs included depression, pelvic limb ataxia, inability to stand without assistance, and pain on deep palpation of the cervical and lumbar vertebral column. Lesions were found in the myocardium, liver, spleen, adrenal glands, brain, and spinal cord. Tachyzoites of Neospora caninum were found in the myocardium and adrenal glands. Organisms stained with anti-Neospora caninum, but not to anti-Toxoplasma gondii serum in an immunohistochemical test.
在一只10岁已绝育的雄性巴吉度猎犬身上发现了自然发生的伴有多器官受累的新孢子虫病。转诊前3周首次注意到临床症状，包括蹲伏姿势和轻度后肢共济失调。给予地塞米松后症状有短暂改善。到教学医院就诊时，临床症状包括精神沉郁、后肢共济失调、无法自主站立以及颈部和腰椎深部触诊疼痛。在心肌、肝脏、脾脏、肾上腺、脑和脊髓中发现了病变。在心肌和肾上腺中发现了犬新孢子虫速殖子。在免疫组织化学检测中，这些病原体能被抗犬新孢子虫血清染色，但不能被抗刚地弓形虫血清染色。
