Dietel Manfred, Schäfer Reinhold
Department of Pathology, Charité-University Medicine Berlin, Charitéplatz 1, 10117, Berlin, Germany.
Virchows Arch. 2008 Oct;453(4):309-12. doi: 10.1007/s00428-008-0656-z. Epub 2008 Sep 13.
To understand the extreme complexity of biological events requires a systemic approach. This holds particularly for the disordered biological interactions that are characteristic of disease, the subject of pathology. Which options are available to untie the Gordian knot? In this contribution, the potential role of systems biology and, as a further development, systems pathology will be discussed.
要理解生物事件的极端复杂性需要一种系统的方法。这一点在疾病所特有的紊乱生物相互作用（病理学的研究对象）方面尤为适用。有哪些方法可以解开这一难题呢？在本文中，将讨论系统生物学以及作为其进一步发展的系统病理学的潜在作用。
