Deveci Artuner, Esen-Danaci Ayşen, Yurtsever Fatma, Deniz Filiz, Gürlek Yüksel Ebru
Turk Psikiyatri Derg. 2008 Fall;19(3):266-73.
The aim of this study was to determine the effect of psychosocial skills training (PST) on symptomatology, insight, quality of life, and suicide probability in patients with schizophrenia.
The sample consisted of 22 schizophrenic outpatients diagnosed according to DSM-IV diagnostic criteria. Three PST groups were formed and each group's training lasted approximately 6 months. Nineteen (86%) patients completed the study. The Scale for the Assessment of Positive Symptoms, Scale for the Assessment of Negative Symptoms, Calgary Depression Rating Scale for Schizophrenia, Schedule for Assessing the Three Components of Insight, Quality of Life Scale for Patients with Schizophrenia, and Suicide Probability Scale were administered to the patients before and after PST.
At the end of the study mean score for the Scale for the Assessment of Positive Symptoms score (baseline 8.5+/- +/- 9.9, post-PST 3.4 +/- +/-6.0, P = 0.004), Scale for the Assessment of Negative Symptoms (baseline 33.7 +/- +/-19.3, post-PST 22.1 +/- +/-15.7, P = 0.001), Calgary Depression Rating Scale for Schizophrenia (baseline 4.2 +/- +/-4.1, post-PST 0.7 +/- +/-1.0, P = 0.001), Schedule for Assessing the Three Components of Insight (baseline 11.1 +/- +/-3.4, post-PST 16.2 +/- +/-1.1, P < 0.0001), and Quality of Life Scale for Patients with Schizophrenia (baseline 53.5 +/- +/-20.0, post-PST 79.6 +/- +/-20.8, P < 0.0001) changed significantly, whereas the change in mean score for the Suicide Probability Scale (baseline 75.1+/- +/- 11.7, post-PST 71.3+/- +/- 8.0, P = 0.06) did not reach statistical significance.
This study demonstrated the effects of PST on the symptoms and functioning of patients with schizophrenia. It can be concluded that using PST for the treatment of schizophrenia, as an adjuvant to pharmacotherapy, could produce significant positive results.
本研究旨在确定心理社会技能训练（PST）对精神分裂症患者症状、洞察力、生活质量和自杀可能性的影响。
样本包括22名根据《精神疾病诊断与统计手册》第四版（DSM-IV）诊断标准确诊的精神分裂症门诊患者。形成了三个PST组，每组训练持续约6个月。19名（86%）患者完成了研究。在PST前后，对患者进行阳性症状评定量表、阴性症状评定量表、精神分裂症卡尔加里抑郁评定量表、洞察力三个成分评定量表、精神分裂症患者生活质量量表和自杀可能性量表的测评。
研究结束时，阳性症状评定量表评分（基线8.5±9.9，PST后3.4±6.0，P = 0.004）、阴性症状评定量表（基线33.7±19.3，PST后22.1±15.7，P = 0.001）、精神分裂症卡尔加里抑郁评定量表（基线4.2±4.1，PST后0.7±1.0，P = 0.001）、洞察力三个成分评定量表（基线11.1±3.4，PST后16.2±1.1，P < 0.0001）和精神分裂症患者生活质量量表（基线53.5±20.0，PST后79.6±20.8，P < 0.0001）的平均得分有显著变化，而自杀可能性量表平均得分的变化（基线75.1±11.7，PST后71.3±8.0，P = 0.06）未达到统计学意义。
本研究证明了PST对精神分裂症患者症状和功能的影响。可以得出结论，将PST作为药物治疗的辅助手段用于精神分裂症的治疗，可能会产生显著的积极效果。
