[II型或III型根治性胃癌切除术（R2、R3）的选择及其5年生存率]

[Choice of radical gastrectomy type II or III (R2, R3) for gastric cancer and its 5-year survival rate].

作者信息

Zhang W F

机构信息

Cancer Institute, China University of Medical Sciences, Shengyang.

出版信息

Zhonghua Zhong Liu Za Zhi. 1991 Mar;13(2):135-8.

PMID:1879291

Abstract

Of 453 patients with primary gastric cancer, 364 were treated from 1979 to 1988 by radical gastrectomy type R2 or R3. The 1-year survival rate was 96.2% (329/342), 3-year survival rate 83.2% (283/286) and 5-year survival rate 58.5% (86/147). This 5-year survival rate has significantly been improved as compared with that of our previous reports in 1964 (19.6%) and 1972 (39.5%) as well as those from other institutes in China (30-40%). The improvement of treatment result is due to: 1. Adequate selection and application of radical gastrectomy, Type II or III operation and thorough resection of lymph node (N2, N3) metastasis and abdominal wall invasion, 2. Increased incidence of early lesions, and 3. better follow-up. TNM classification, histologic growth pattern, lymph node metastasis, gross type and site of primary cancer all play significant roles in prognosis.

摘要

在453例原发性胃癌患者中，1979年至1988年期间有364例行R2或R3根治性胃切除术。1年生存率为96.2%（329/342），3年生存率为83.2%（283/286），5年生存率为58.5%（86/147）。与我们1964年（19.6%）和1972年（39.5%）的既往报告以及中国其他机构的报告（30%-40%）相比，这一5年生存率有显著提高。治疗效果的改善归因于：1. 根治性胃切除术、II型或III型手术的充分选择和应用，以及对淋巴结（N2、N3）转移和腹壁侵犯的彻底切除；2. 早期病变发生率增加；3. 更好的随访。TNM分类、组织学生长模式、淋巴结转移、大体类型和原发癌部位在预后中均起重要作用。